C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cystic fibrosis transmembrane conductance regulator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000115405 Cftr-004 ENSMUSG00000041301 10090 + 6:18170687-18322767 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainTestisENSMUST00000115405
Transcript ID Brain Testis
ENSMUST00000115405 0.026±0.00 1.586±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00063R CIL_00063R_0003 CGP 6:18050964-18322768
CIL_0005U6 CIL_0005U6_0003 CGP 6:18170687-18514869

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005254 ISS chloride channel activity
GO:0005260 IEA channel-conductance-controlling ATPase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005769 ISS early endosome
GO:0005886 ISS plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006695 IMP cholesterol biosynthetic process
GO:0006821 IGI chloride transport
GO:0015106 IMP bicarbonate transmembrane transporter activity
GO:0015108 IMP chloride transmembrane transporter activity
GO:0019869 ISS chloride channel inhibitor activity
GO:0030301 IMP cholesterol transport
GO:0034707 IEA chloride channel complex
GO:0048240 IMP sperm capacitation
GO:0051454 IMP intracellular pH elevation
GO:0060081 IMP membrane hyperpolarization
GO:0071320 IDA cellular response to cAMP
GO:1902476 IEA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000003084 CFTR-001 protein_coding Homo_sapiens 0 2124
ENST00000426809 CFTR-005 protein_coding Homo_sapiens 0 2091
ENST00000468795 CFTR-002 protein_coding Homo_sapiens 0 494
ENST00000600166 CFTR-008 protein_coding Homo_sapiens 0 364

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