C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SRY (sex determining region Y)-box 17
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000116652 Sox17-202 ENSMUSG00000025902 10090 - 1:4491713-4496363 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaENSMUST00000116652
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta
ENSMUST00000116652 23.432±12.03 27.742±8.06 4.566±0.06 3.637±1.55 5.142±2.65 1.363±0.45 1.318±0.00 6.562±4.13 1.350±0.85 13.440±0.00 42.072±14.64 7.642±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00053S CIL_00053S_0002 CGP 1:4490928-4785739

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001525 IGI angiogenesis
GO:0001570 IGI vasculogenesis
GO:0001828 IMP inner cell mass cellular morphogenesis
GO:0001947 IMP heart looping
GO:0003142 IMP cardiogenic plate morphogenesis
GO:0003143 IMP embryonic heart tube morphogenesis
GO:0003151 IGI outflow tract morphogenesis
GO:0003308 IMP negative regulation of Wnt signaling pathway involved in heart development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007283 IDA spermatogenesis
GO:0007369 IMP gastrulation
GO:0007492 IMP endoderm development
GO:0007493 IDA endodermal cell fate determination
GO:0010628 IMP positive regulation of gene expression
GO:0021903 IMP rostrocaudal neural tube patterning
GO:0023019 IDA signal transduction involved in regulation of gene expression
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0035050 IGI embryonic heart tube development
GO:0042074 IMP cell migration involved in gastrulation
GO:0042661 IMP regulation of mesodermal cell fate specification
GO:0042662 IMP negative regulation of mesodermal cell fate specification
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045595 IMP regulation of cell differentiation
GO:0045597 IDA positive regulation of cell differentiation
GO:0045732 IDA positive regulation of protein catabolic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045995 IMP regulation of embryonic development
GO:0046982 IDA protein heterodimerization activity
GO:0048568 IMP embryonic organ development
GO:0048617 IMP embryonic foregut morphogenesis
GO:0048643 IDA positive regulation of skeletal muscle tissue development
GO:0048863 IMP stem cell differentiation
GO:0048866 IDA stem cell fate specification
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060214 IGI endocardium formation
GO:0060807 IMP regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification
GO:0060956 IGI endocardial cell differentiation
GO:0061009 IMP common bile duct development
GO:0061010 IMP gall bladder development
GO:0061031 IMP endodermal digestive tract morphogenesis
GO:0072091 IDA regulation of stem cell proliferation
GO:2000035 IMP regulation of stem cell division
GO:2000043 IMP regulation of cardiac cell fate specification

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000297316 SOX17-001 protein_coding Homo_sapiens 0 1155
ENST00000340356 SOX18-001 protein_coding Homo_sapiens 0 254

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