C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SRY (sex determining region Y)-box 18
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000340356 SOX18-001 ENSG00000203883 9606 - 20:64047582-64049641 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000340356
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000340356 15.331±0.00 37.997±0.00 7.367±0.00 23.960±0.00 7.986±0.00 24.752±0.00 11.333±0.00 3.750±0.00 32.167±0.00 22.042±0.00 26.191±0.00 25.443±3.56 9.440±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004F5 CIL_0004F5_0001 CGP 20:63939829-64048758
CIL_0003V3 CIL_0003V3_0001 CGP 20:64047582-64072347

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IEP angiogenesis
GO:0001568 IEA blood vessel development
GO:0001570 ISS vasculogenesis
GO:0001701 IEA in utero embryonic development
GO:0001942 IEA hair follicle development
GO:0001944 ISS vasculature development
GO:0001945 IEA lymph vessel development
GO:0001946 IMP lymphangiogenesis
GO:0001947 ISS heart looping
GO:0003151 ISS outflow tract morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007507 IEA heart development
GO:0022405 IMP hair cycle process
GO:0035050 ISS embryonic heart tube development
GO:0042789 IDA mRNA transcription from RNA polymerase II promoter
GO:0043534 IEP blood vessel endothelial cell migration
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IEA nuclear transcription factor complex
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0048469 IEA cell maturation
GO:0048866 IEA stem cell fate specification
GO:0060214 ISS endocardium formation
GO:0060836 ISS lymphatic endothelial cell differentiation
GO:0060956 ISS endocardial cell differentiation
GO:0061028 IMP establishment of endothelial barrier
GO:0072091 IEA regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000054491 Sox18-001 protein_coding Mus_musculus 0 1107
ENSMUST00000116652 Sox17-202 protein_coding Mus_musculus 0 254
ENSMUST00000027035 Sox17-201 protein_coding Mus_musculus 0 254
ENSMUST00000170662 Sox21-001 protein_coding Mus_musculus 1e-19 102
ENSMUST00000180353 Sox1-001 protein_coding Mus_musculus 7e-17 94
ENSMUST00000040019 Sox10-201 protein_coding Mus_musculus 0.000000000002 79
ENSMUST00000047373 Sox15-001 protein_coding Mus_musculus 0.000000000007 77

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