C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000117291 Mthfd1l-001 ENSMUSG00000040675 10090 + 10:3973118-4156111 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000117291
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000117291 0.547±0.44 4.512±0.24 1.355±0.31 0.736±0.47 0.607±0.19 0.161±0.03 0.261±0.11 10.280±6.05 0.609±0.16 0.151±0.05 1.957±0.95 8.185±4.07 0.487±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005ED CIL_0005ED_0002 CGP 10:3740364-4167081
CIL_0005EE CIL_0005EE_0002 CGP 10:3973118-4359468

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004329 IBA formate-tetrahydrofolate ligase activity
GO:0004488 IEA methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005524 IEA ATP binding
GO:0005739 ISO mitochondrion
GO:0006730 IBA one-carbon metabolic process
GO:0009257 ISO 10-formyltetrahydrofolate biosynthetic process
GO:0035999 IEA tetrahydrofolate interconversion
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000367308 MTHFD1L-008 protein_coding Homo_sapiens 0 688
ENST00000367321 MTHFD1L-003 protein_coding Homo_sapiens 0 2859
ENST00000421497 MTHFD1L-005 processed_transcript Homo_sapiens 0.00000000000003 82
ENST00000441122 MTHFD1L-004 nonsense_mediated_decay Homo_sapiens 0 573
ENST00000478643 MTHFD1L-006 processed_transcript Homo_sapiens 1e-37 159
ENST00000611279 MTHFD1L-201 protein_coding Homo_sapiens 0 2850
ENST00000618312 MTHFD1L-202 protein_coding Homo_sapiens 0 2796

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