C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: cyclin-dependent kinase inhibitor 1A (P21)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000119901 Cdkn1a-003 ENSMUSG00000023067 10090 + 17:29090979-29099527 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalENSMUST00000119901
Transcript ID Adrenal
ENSMUST00000119901 7.589±1.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002YD CIL_0002YD_0002 CGP 17:29090979-29148980

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000079 IMP regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000307 IPI cyclin-dependent protein kinase holoenzyme complex
GO:0004861 IDA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007050 IDA cell cycle arrest
GO:0007346 IMP regulation of mitotic cell cycle
GO:0008285 IMP negative regulation of cell proliferation
GO:0009411 IMP response to UV
GO:0010629 IMP negative regulation of gene expression
GO:0030332 IDA cyclin binding
GO:0030890 IGI positive regulation of B cell proliferation
GO:0033158 IMP regulation of protein import into nucleus, translocation
GO:0042771 IMP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043068 IMP positive regulation of programmed cell death
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0046872 IEA metal ion binding
GO:0051726 IDA regulation of cell cycle
GO:0070557 ISS PCNA-p21 complex
GO:0071850 IDA mitotic cell cycle arrest
GO:2000278 IMP regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000244741 CDKN1A-001 protein_coding Homo_sapiens 0 309
ENST00000373711 CDKN1A-002 protein_coding Homo_sapiens 0 309
ENST00000405375 CDKN1A-201 protein_coding Homo_sapiens 0 309
ENST00000448526 CDKN1A-202 protein_coding Homo_sapiens 0 309
ENST00000615513 CDKN1A-203 protein_coding Homo_sapiens 0 309

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