C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: receptor tyrosine kinase-like orphan receptor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000130235 Ror2-002 ENSMUSG00000021464 10090 - 13:53109312-53285549 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000130235
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000130235 0.515±0.02 1.829±0.45 0.133±0.00 0.985±0.51 2.272±1.18 0.293±0.00 0.605±0.00 0.056±0.04 0.720±0.00 0.085±0.03 1.607±0.54 0.452±0.08 0.820±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00068R CIL_00068R_0002 CGP 13:52967209-53286124
CIL_0002JG CIL_0002JG_0002 CGP 13:53109312-53377365

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001502 IMP cartilage condensation
GO:0001756 IMP somitogenesis
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0005109 IPI frizzled binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 ISS integral component of plasma membrane
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007223 IPI Wnt signaling pathway, calcium modulating pathway
GO:0007254 IDA JNK cascade
GO:0017147 IPI Wnt-protein binding
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030154 IMP cell differentiation
GO:0030538 IMP embryonic genitalia morphogenesis
GO:0042472 IMP inner ear morphogenesis
GO:0060071 IMP Wnt signaling pathway, planar cell polarity pathway
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000375708 ROR2-001 protein_coding Homo_sapiens 0 3249
ENST00000375715 ROR2-002 protein_coding Homo_sapiens 0 2704
ENST00000550066 ROR2-006 processed_transcript Homo_sapiens 0 3254

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