C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000143601 Lrp8-001 ENSMUSG00000028613 10090 + 4:107802261-107874167 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonHeartOvaryENSMUST00000143601
Transcript ID Colon Heart Ovary
ENSMUST00000143601 0.310±0.00 0.143±0.00 1.150±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00083F CIL_00083F_0002 VISTA 4:107302048-107904613

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001948 IPI glycoprotein binding
GO:0005041 TAS low-density lipoprotein receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0006897 ISS endocytosis
GO:0006898 TAS receptor-mediated endocytosis
GO:0016021 IEA integral component of membrane
GO:0021517 IEP ventral spinal cord development
GO:0021541 IMP ammon gyrus development
GO:0021766 IGI hippocampus development
GO:0021819 IGI layer formation in cerebral cortex
GO:0032793 IMP positive regulation of CREB transcription factor activity
GO:0034185 IDA apolipoprotein binding
GO:0038025 IMP reelin receptor activity
GO:0038026 IMP reelin-mediated signaling pathway
GO:0043235 ISO receptor complex
GO:0045860 IGI positive regulation of protein kinase activity
GO:0048306 IPI calcium-dependent protein binding
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0050804 IMP regulation of synaptic transmission
GO:0061003 IMP positive regulation of dendritic spine morphogenesis
GO:0061098 IMP positive regulation of protein tyrosine kinase activity
GO:1900006 IGI positive regulation of dendrite development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000306052 LRP8-001 protein_coding Homo_sapiens 0 2484
ENST00000347547 LRP8-011 protein_coding Homo_sapiens 0 2414
ENST00000354412 LRP8-003 protein_coding Homo_sapiens 0 1559
ENST00000371454 LRP8-002 protein_coding Homo_sapiens 0 2073
ENST00000459674 LRP8-006 retained_intron Homo_sapiens 0 1681
ENST00000460214 LRP8-007 processed_transcript Homo_sapiens 0 689
ENST00000465675 LRP8-004 protein_coding Homo_sapiens 0 1762
ENST00000475501 LRP8-009 protein_coding Homo_sapiens 0 802
ENST00000480045 LRP8-005 nonsense_mediated_decay Homo_sapiens 0 3827
ENST00000481431 LRP8-008 nonsense_mediated_decay Homo_sapiens 0 416
ENST00000613948 LRP8-201 protein_coding Homo_sapiens 0 1539

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