C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000306052 LRP8-001 ENSG00000157193 9606 - 1:53245539-53328014 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000306052
Transcript ID Adipose Brain Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000306052 0.468±0.00 2.117±0.36 0.265±0.00 0.073±0.06 0.202±0.00 0.071±0.02 0.310±0.00 2.185±0.00 0.815±0.00 9.417±3.87

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001523 TAS retinoid metabolic process
GO:0004888 TAS transmembrane signaling receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 IEA extracellular region
GO:0005875 IEA microtubule associated complex
GO:0005886 TAS plasma membrane
GO:0005901 IDA caveola
GO:0006508 NAS proteolysis
GO:0006629 NAS lipid metabolic process
GO:0006897 IDA endocytosis
GO:0006898 IDA receptor-mediated endocytosis
GO:0007165 TAS signal transduction
GO:0007596 TAS blood coagulation
GO:0007603 TAS phototransduction, visible light
GO:0008035 IEA high-density lipoprotein particle binding
GO:0014069 IEA postsynaptic density
GO:0016020 IDA membrane
GO:0016021 IC integral component of membrane
GO:0019221 NAS cytokine-mediated signaling pathway
GO:0019894 IEA kinesin binding
GO:0021541 ISS ammon gyrus development
GO:0021766 IEA hippocampus development
GO:0021819 IEA layer formation in cerebral cortex
GO:0021987 IEA cerebral cortex development
GO:0030229 IDA very-low-density lipoprotein particle receptor activity
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0032793 ISS positive regulation of CREB transcription factor activity
GO:0034185 IC apolipoprotein binding
GO:0038025 ISS reelin receptor activity
GO:0038026 ISS reelin-mediated signaling pathway
GO:0042493 IEA response to drug
GO:0043025 IEA neuronal cell body
GO:0043235 IDA receptor complex
GO:0045860 IEA positive regulation of protein kinase activity
GO:0050731 ISS positive regulation of peptidyl-tyrosine phosphorylation
GO:0050804 ISS regulation of synaptic transmission
GO:0061003 ISS positive regulation of dendritic spine morphogenesis
GO:0061098 ISS positive regulation of protein tyrosine kinase activity
GO:0071363 IEA cellular response to growth factor stimulus
GO:0071397 IEA cellular response to cholesterol
GO:1900006 ISS positive regulation of dendrite development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000030356 Lrp8-006 protein_coding Mus_musculus 0 3670
ENSMUST00000106733 Lrp8-007 protein_coding Mus_musculus 0 3182
ENSMUST00000123140 Lrp8-004 processed_transcript Mus_musculus 0 2885
ENSMUST00000143601 Lrp8-001 nonsense_mediated_decay Mus_musculus 0 2484
ENSMUST00000106732 Lrp8-002 protein_coding Mus_musculus 0 2459
ENSMUST00000106731 Lrp8-003 protein_coding Mus_musculus 0 2182
ENSMUST00000146552 Lrp8-009 processed_transcript Mus_musculus 0 1764
ENSMUST00000126573 Lrp8-008 protein_coding Mus_musculus 0 1668
ENSMUST00000135022 Lrp8-012 processed_transcript Mus_musculus 0 819
ENSMUST00000135591 Lrp8-011 retained_intron Mus_musculus 0 544

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