C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lamin A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000149068 Lmna-004 ENSMUSG00000028063 10090 - 3:88502753-88509956 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonKidneyLungOvaryENSMUST00000149068
Transcript ID Adipose Adrenal Breast Colon Kidney Lung Ovary
ENSMUST00000149068 40.982±2.56 72.353±22.56 76.381±18.66 186.067±35.32 15.095±0.71 46.740±9.84 101.344±16.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P5 CIL_0008P5_0002 VISTA 3:88218217-88823366
CIL_000898 CIL_000898_0002 VISTA 3:88224783-88827970

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005638 IDA lamin filament
GO:0006997 IMP nucleus organization
GO:0006998 IGI nuclear envelope organization
GO:0034504 IMP protein localization to nucleus
GO:0035105 IMP sterol regulatory element binding protein import into nucleus
GO:0055015 IMP ventricular cardiac muscle cell development
GO:0090201 IMP negative regulation of release of cytochrome c from mitochondria
GO:1900180 IMP regulation of protein localization to nucleus
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000347559 LMNA-201 protein_coding Homo_sapiens 0 688
ENST00000361308 LMNA-202 protein_coding Homo_sapiens 0 688
ENST00000368299 LMNA-004 protein_coding Homo_sapiens 0 634
ENST00000368300 LMNA-001 protein_coding Homo_sapiens 0 652
ENST00000368301 LMNA-002 protein_coding Homo_sapiens 0 643
ENST00000469565 LMNA-025 processed_transcript Homo_sapiens 0 420
ENST00000470199 LMNA-023 processed_transcript Homo_sapiens 0 357
ENST00000478063 LMNA-024 processed_transcript Homo_sapiens 2e-24 115

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