C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate-cysteine ligase, modifier subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000149983 Gclm-002 ENSMUSG00000028124 10090 + 3:122255587-122266503 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; PlacentaTestisENSMUST00000149983
Transcript ID Placenta Testis
ENSMUST00000149983 14.181±0.00 3.985±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DI CIL_0009DI_0002 VISTA 3:121653542-122254391
CIL_0009DJ CIL_0009DJ_0002 VISTA 3:121747471-122349247
CIL_0009DH CIL_0009DH_0002 VISTA 3:121992915-122594267
CIL_00005U CIL_00005U_0002 CGP 3:122245557-122285269

Gene Ontology

GO IDEvidence TypeGO Description
GO:0006534 IMP cysteine metabolic process
GO:0006749 IMP glutathione metabolic process
GO:0006750 IDA glutathione biosynthetic process
GO:0006979 IMP response to oxidative stress
GO:0008637 IGI apoptotic mitochondrial changes
GO:0017109 IDA glutamate-cysteine ligase complex
GO:0035226 IDA glutamate-cysteine ligase catalytic subunit binding
GO:0035229 IDA positive regulation of glutamate-cysteine ligase activity
GO:0046982 IPI protein heterodimerization activity
GO:0051900 IGI regulation of mitochondrial depolarization
GO:2001237 IGI negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000370238 GCLM-001 protein_coding Homo_sapiens 0 532
ENST00000467772 GCLM-002 processed_transcript Homo_sapiens 0 532
ENST00000615724 GCLM-201 protein_coding Homo_sapiens 0 507
ENST00000619076 GCLM-202 protein_coding Homo_sapiens 0 300

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