C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribosomal protein S6 kinase, polypeptide 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000154617 Rps6kb1-001 ENSMUSG00000020516 10090 - 11:86498871-86544805 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000154617
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000154617 4.620±0.70 1.994±0.52 7.463±0.27 7.688±3.45 3.605±0.42 1.784±0.36 2.696±0.41 2.656±0.57 4.603±2.64 3.561±0.60 5.043±0.36 3.140±1.53 3.716±1.72 1.274±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039N CIL_00039N_0002 CGP 11:86267033-86499025
CIL_0008VS CIL_0008VS_0002 VISTA 11:86270110-86871719
CIL_0008Y2 CIL_0008Y2_0002 VISTA 11:86286196-86887829
CIL_00081F CIL_00081F_0002 VISTA 11:86323484-86925483

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0003009 IEA skeletal muscle contraction
GO:0004672 IDA protein kinase activity
GO:0004711 IEA ribosomal protein S6 kinase activity
GO:0004712 ISO protein serine/threonine/tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007281 IDA germ cell development
GO:0007568 IEA aging
GO:0007584 IEA response to nutrient
GO:0007616 IEA long-term memory
GO:0009408 IEA response to heat
GO:0009611 IEA response to wounding
GO:0009612 IEA response to mechanical stimulus
GO:0009636 IEA response to toxic substance
GO:0009749 IEA response to glucose
GO:0009986 IEA cell surface
GO:0010033 IEA response to organic substance
GO:0014070 IEA response to organic cyclic compound
GO:0014732 IEA skeletal muscle atrophy
GO:0014878 IEA response to electrical stimulus involved in regulation of muscle adaptation
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0016477 IEA cell migration
GO:0030054 IEA cell junction
GO:0031929 IEA TOR signaling
GO:0032496 IEA response to lipopolysaccharide
GO:0032868 IEA response to insulin
GO:0032870 IEA cellular response to hormone stimulus
GO:0033574 IEA response to testosterone
GO:0033762 IEA response to glucagon
GO:0034612 IEA response to tumor necrosis factor
GO:0042277 IEA peptide binding
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043066 ISS negative regulation of apoptotic process
GO:0043200 IEA response to amino acid
GO:0043201 IEA response to leucine
GO:0043434 IEA response to peptide hormone
GO:0043491 IGI protein kinase B signaling
GO:0045202 IEA synapse
GO:0045471 IEA response to ethanol
GO:0045727 IEA positive regulation of translation
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0045948 IEA positive regulation of translational initiation
GO:0046324 IEA regulation of glucose import
GO:0046627 IEA negative regulation of insulin receptor signaling pathway
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048633 IEA positive regulation of skeletal muscle tissue growth
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051384 IEA response to glucocorticoid
GO:0071363 ISS cellular response to growth factor stimulus
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000225577 RPS6KB1-001 protein_coding Homo_sapiens 0 3531
ENST00000393021 RPS6KB1-201 protein_coding Homo_sapiens 0 3284
ENST00000406116 RPS6KB1-002 protein_coding Homo_sapiens 0 2150
ENST00000441215 AC126365.1-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 1500
ENST00000443572 RPS6KB1-008 protein_coding Homo_sapiens 0 1895
ENST00000472940 RPS6KB1-003 nonsense_mediated_decay Homo_sapiens 0 1315
ENST00000475155 RPS6KB1-006 retained_intron Homo_sapiens 0 580
ENST00000477179 RPS6KB1-005 processed_transcript Homo_sapiens 0 616
ENST00000489824 RPS6KB1-004 nonsense_mediated_decay Homo_sapiens 0 684
ENST00000577881 RP11-51L5.3-001 unprocessed_pseudogene Homo_sapiens 0 1166
ENST00000578210 AC126365.1-002 processed_transcript Homo_sapiens 0 307
ENST00000587061 RPS6KB1-011 processed_transcript Homo_sapiens 0 243
ENST00000587622 RPS6KB1-009 retained_intron Homo_sapiens 0 477
ENST00000590928 RPS6KB1-010 retained_intron Homo_sapiens 0 313
ENST00000591035 RP11-178C3.1-001 protein_coding Homo_sapiens 0 237
ENST00000592726 RPS6KB1-007 protein_coding Homo_sapiens 0 381

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