C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribosomal protein S6 kinase, 70kDa, polypeptide 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000393021 RPS6KB1-201 ENSG00000108443 9606 + 17:59893046-59950421 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393021
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393021 4.040±0.00 3.780±0.00 2.532±1.82 4.738±0.00 2.287±0.00 2.056±1.24 2.862±0.00 2.032±0.00 3.437±0.41 5.424±0.00 2.399±0.73 1.103±0.10 3.585±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081F CIL_00081F_0001 VISTA 17:59485788-60087415
CIL_0008Y2 CIL_0008Y2_0001 VISTA 17:59536739-60138754
CIL_0008VS CIL_0008VS_0001 VISTA 17:59556856-60159441
CIL_00056A CIL_00056A_0002 CGP 17:59859482-59950564

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004712 IDA protein serine/threonine/tyrosine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0005829 TAS cytosol
GO:0006468 IDA:IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007165 TAS:IEA signal transduction
GO:0008286 TAS insulin receptor signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030054 IEA cell junction
GO:0031929 IDA TOR signaling
GO:0043005 IEA neuron projection
GO:0043066 IMP negative regulation of apoptotic process
GO:0045202 IEA synapse
GO:0045727 IMP positive regulation of translation
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0045948 IMP positive regulation of translational initiation
GO:0046627 IMP negative regulation of insulin receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling
GO:0071363 IDA cellular response to growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000154617 Rps6kb1-001 protein_coding Mus_musculus 0 3284
ENSMUST00000020824 Rps6kb1-004 retained_intron Mus_musculus 0 1315
ENSMUST00000138810 Rps6kb1-005 protein_coding Mus_musculus 0 883
ENSMUST00000058286 Rps6kb1-002 protein_coding Mus_musculus 0 684
ENSMUST00000149392 Rps6kb1-006 processed_transcript Mus_musculus 0 555
ENSMUST00000151748 Rps6kb1-007 retained_intron Mus_musculus 0 276
ENSMUST00000131194 Rps6kb1-003 processed_transcript Mus_musculus 0 243

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