C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ribosomal protein S6 kinase, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020516 Rps6kb1 10090 - 11:86498871-86544805 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020824 Rps6kb1-004 86502033-86544805 retained_intron
  ENSMUST00000058286 Rps6kb1-002 86513983-86544774 protein_coding
  ENSMUST00000131194 Rps6kb1-003 86513618-86520039 processed_transcript
  ENSMUST00000138810 Rps6kb1-005 86532772-86544765 protein_coding
  ENSMUST00000149392 Rps6kb1-006 86502599-86511645 processed_transcript
  ENSMUST00000151748 Rps6kb1-007 86519644-86532840 retained_intron
  ENSMUST00000154617 Rps6kb1-001 86498871-86544805 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020824ENSMUST00000138810ENSMUST00000149392ENSMUST00000154617
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020824 3.033±0.28 N/A N/A N/A 2.068±0.26 1.438±0.00 1.719±0.19 2.143±0.00 1.902±0.00 2.258±0.22 N/A 4.928±0.10 5.736±1.94 N/A
ENSMUST00000138810 N/A 14.092±3.37 N/A N/A N/A 6.895±1.65 N/A N/A 9.292±0.47 5.224±0.00 N/A 7.918±0.23 N/A N/A
ENSMUST00000149392 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.567±0.00 N/A N/A
ENSMUST00000154617 4.620±0.70 1.994±0.52 7.463±0.27 7.688±3.45 3.605±0.42 1.784±0.36 2.696±0.41 2.656±0.57 4.603±2.64 3.561±0.60 5.043±0.36 3.140±1.53 3.716±1.72 1.274±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00039N CIL_00039N_0002 CGP 11:86267033-86499025
CIL_0008VS CIL_0008VS_0002 VISTA 11:86270110-86871719
CIL_0008Y2 CIL_0008Y2_0002 VISTA 11:86286196-86887829
CIL_00081F CIL_00081F_0002 VISTA 11:86323484-86925483

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0003009 IEA skeletal muscle contraction
GO:0004672 IDA protein kinase activity
GO:0004711 IEA ribosomal protein S6 kinase activity
GO:0004712 ISO protein serine/threonine/tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007281 IDA germ cell development
GO:0007568 IEA aging
GO:0007584 IEA response to nutrient
GO:0007616 IEA long-term memory
GO:0009408 IEA response to heat
GO:0009611 IEA response to wounding
GO:0009612 IEA response to mechanical stimulus
GO:0009636 IEA response to toxic substance
GO:0009749 IEA response to glucose
GO:0009986 IEA cell surface
GO:0010033 IEA response to organic substance
GO:0014070 IEA response to organic cyclic compound
GO:0014732 IEA skeletal muscle atrophy
GO:0014878 IEA response to electrical stimulus involved in regulation of muscle adaptation
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0016477 IEA cell migration
GO:0030054 IEA cell junction
GO:0031929 IEA TOR signaling
GO:0032496 IEA response to lipopolysaccharide
GO:0032868 IEA response to insulin
GO:0032870 IEA cellular response to hormone stimulus
GO:0033574 IEA response to testosterone
GO:0033762 IEA response to glucagon
GO:0034612 IEA response to tumor necrosis factor
GO:0042277 IEA peptide binding
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043066 ISS negative regulation of apoptotic process
GO:0043200 IEA response to amino acid
GO:0043201 IEA response to leucine
GO:0043434 IEA response to peptide hormone
GO:0043491 IGI protein kinase B signaling
GO:0045202 IEA synapse
GO:0045471 IEA response to ethanol
GO:0045727 IEA positive regulation of translation
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0045948 IEA positive regulation of translational initiation
GO:0046324 IEA regulation of glucose import
GO:0046627 IEA negative regulation of insulin receptor signaling pathway
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048633 IEA positive regulation of skeletal muscle tissue growth
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051384 IEA response to glucocorticoid
GO:0071363 ISS cellular response to growth factor stimulus
GO:2001237 IMP negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058230 rps6kb1b ribosomal protein S6 kinase b, polypeptide 1b protein_coding Danio_rerio
ENSG00000108443 RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 protein_coding Homo_sapiens

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