C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fragile histidine triad gene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000160340 Fhit-002 ENSMUSG00000060579 10090 - 14:9550100-11162035 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalHeartMuscleTestisENSMUST00000160340
Transcript ID Adrenal Heart Muscle Testis
ENSMUST00000160340 0.369±0.03 0.283±0.19 0.251±0.00 0.290±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00034H CIL_00034H_0002 CGP 14:8431192-11162035

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003824 TAS catalytic activity
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0006163 ISS purine nucleotide metabolic process
GO:0006260 IDA DNA replication
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0009117 TAS nucleotide metabolic process
GO:0016787 IDA hydrolase activity
GO:0032435 ISS negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0047710 IDA bis(5'-adenosyl)-triphosphatase activity
GO:0072332 ISS intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000110845 fhit-001 protein_coding Danio_rerio 3e-33 147
ENSDART00000099715 fhit-201 protein_coding Danio_rerio 1e-31 141
ENST00000468189 FHIT-002 protein_coding Homo_sapiens 0 492
ENST00000476844 FHIT-001 protein_coding Homo_sapiens 0 492
ENST00000488467 FHIT-007 protein_coding Homo_sapiens 0 302
ENST00000490952 FHIT-004 retained_intron Homo_sapiens 2e-31 141
ENST00000492590 FHIT-003 protein_coding Homo_sapiens 0 492

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