C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase 5, regulatory subunit 2 (p39)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000160379 Cdk5r2-001 ENSMUSG00000090071 10090 + 1:74854934-74857732 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000160379
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000160379 0.033±0.01 2.682±0.65 0.034±0.02 26.840±4.42 0.023±0.00 1.054±0.11 0.038±0.02 0.088±0.04 0.014±0.01 0.030±0.01 0.172±0.10 0.036±0.02 0.031±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001I8 CIL_0001I8_0003 CGP 1:74791516-74857732
CIL_0001I5 CIL_0001I5_0003 CGP 1:74854934-74885419

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IGI neuron migration
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0008092 TAS cytoskeletal protein binding
GO:0008289 IEA lipid binding
GO:0016533 IEA cyclin-dependent protein kinase 5 holoenzyme complex
GO:0016534 IMP cyclin-dependent protein kinase 5 activator activity
GO:0021549 IGI cerebellum development
GO:0021722 IGI superior olivary nucleus maturation
GO:0021766 IGI hippocampus development
GO:0021819 IGI layer formation in cerebral cortex
GO:0045860 IGI positive regulation of protein kinase activity
GO:0045956 IDA positive regulation of calcium ion-dependent exocytosis
GO:0071902 IEA positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000302625 CDK5R2-001 protein_coding Homo_sapiens 0 2021
ENST00000313401 CDK5R1-001 protein_coding Homo_sapiens 0 265
ENST00000584716 CDK5R1-002 nonsense_mediated_decay Homo_sapiens 3e-33 147
ENST00000584792 CDK5R1-003 protein_coding Homo_sapiens 2e-33 147

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