C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: topoisomerase (DNA) II beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000161693 Top2b-006 ENSMUSG00000017485 10090 + 14:16413717-16425437 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000712 IBA resolution of meiotic recombination intermediates
GO:0000819 IBA sister chromatid segregation
GO:0001764 IMP neuron migration
GO:0003918 IBA DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0006200 IEA ATP catabolic process
GO:0006265 IBA DNA topological change
GO:0006268 IBA DNA unwinding involved in DNA replication
GO:0006312 IBA mitotic recombination
GO:0007409 IMP axonogenesis
GO:0008301 IEA DNA binding, bending
GO:0009330 IBA DNA topoisomerase complex (ATP-hydrolyzing)
GO:0030900 IMP forebrain development
GO:0044774 IBA mitotic DNA integrity checkpoint

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264331 TOP2B-201 protein_coding Homo_sapiens 0 878
ENST00000413971 TOP2B-005 nonsense_mediated_decay Homo_sapiens 0 878
ENST00000424225 TOP2B-002 protein_coding Homo_sapiens 0 394
ENST00000435706 TOP2B-001 protein_coding Homo_sapiens 0 878
ENST00000475717 TOP2B-008 processed_transcript Homo_sapiens 0 327

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