C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WW domain containing E3 ubiquitin protein ligase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000166615 Wwp2-201 ENSMUSG00000031930 10090 + 8:107436398-107558594 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000166615
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000166615 10.147±2.16 8.783±2.85 7.476±0.21 11.197±2.71 10.830±2.23 24.598±8.35 5.103±0.81 17.146±1.25 7.359±1.82 16.312±1.25 2.683±0.51 17.478±3.30 9.716±2.82 13.708±9.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KB CIL_0008KB_0002 VISTA 8:107038845-107639359
CIL_00090U CIL_00090U_0002 VISTA 8:107303123-107903792
CIL_0001NB CIL_0001NB_0002 CGP 8:107412486-107558594

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0008134 IEA transcription factor binding
GO:0010629 IEA negative regulation of gene expression
GO:0016020 IEA membrane
GO:0016567 ISS protein ubiquitination
GO:0016874 IEA ligase activity
GO:0032410 IEA negative regulation of transporter activity
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042391 IEA regulation of membrane potential
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043433 IDA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0051224 IEA negative regulation of protein transport
GO:0051865 IEA protein autoubiquitination
GO:0070062 IEA extracellular vesicular exosome
GO:0070534 IMP protein K63-linked ubiquitination
GO:1901016 IEA regulation of potassium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000356003 WWP2-201 protein_coding Homo_sapiens 0 3011
ENST00000359154 WWP2-001 protein_coding Homo_sapiens 0 3487
ENST00000544162 WWP2-002 processed_transcript Homo_sapiens 0 3140
ENST00000561780 WWP2-004 protein_coding Homo_sapiens 0 409
ENST00000563659 WWP2-006 protein_coding Homo_sapiens 0 257
ENST00000566463 WWP2-014 retained_intron Homo_sapiens 0 2263
ENST00000567161 WWP2-018 retained_intron Homo_sapiens 0 490
ENST00000567303 WWP2-019 retained_intron Homo_sapiens 0 516
ENST00000567579 WWP2-013 processed_transcript Homo_sapiens 0 483
ENST00000568185 WWP2-016 processed_transcript Homo_sapiens 6e-18 95
ENST00000568684 WWP2-015 protein_coding Homo_sapiens 0 2052
ENST00000568818 WWP2-017 retained_intron Homo_sapiens 0 339
ENST00000568845 WWP2-003 processed_transcript Homo_sapiens 9e-35 150
ENST00000569174 WWP2-012 protein_coding Homo_sapiens 0 1175
ENST00000569297 WWP2-011 processed_transcript Homo_sapiens 0 2412
ENST00000569620 WWP2-005 nonsense_mediated_decay Homo_sapiens 0 438
ENST00000569658 WWP2-007 retained_intron Homo_sapiens 0 462

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