C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SMAD family member 7
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000168918 Smad7-201 ENSMUSG00000025880 10090 + 18:75368883-75395479 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastHeartKidneyLiverLungMusclePlacentaTestisENSMUST00000168918
Transcript ID Adipose Bladder Breast Heart Kidney Liver Lung Muscle Placenta Testis
ENSMUST00000168918 1.903±0.40 2.147±0.00 3.774±0.71 2.877±0.55 3.823±1.02 1.252±0.25 7.894±1.04 0.761±0.14 4.980±0.90 0.155±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P6 CIL_0008P6_0002 VISTA 18:75201597-75805830
CIL_0007UR CIL_0007UR_0002 VISTA 18:75202363-75803667

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001657 IEP ureteric bud development
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005518 IPI collagen binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0010801 IMP negative regulation of peptidyl-threonine phosphorylation
GO:0017015 IC regulation of transforming growth factor beta receptor signaling pathway
GO:0022409 IMP positive regulation of cell-cell adhesion
GO:0030514 IDA negative regulation of BMP signaling pathway
GO:0033137 IMP negative regulation of peptidyl-serine phosphorylation
GO:0043234 IDA protein complex
GO:0046872 IEA metal ion binding
GO:0048844 IMP artery morphogenesis
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060373 IC regulation of ventricular cardiac muscle cell membrane depolarization
GO:0060389 IMP pathway-restricted SMAD protein phosphorylation
GO:0060412 IMP ventricular septum morphogenesis
GO:0071560 IMP cellular response to transforming growth factor beta stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262158 SMAD7-001 protein_coding Homo_sapiens 0 2176
ENST00000545051 SMAD7-003 retained_intron Homo_sapiens 0 987
ENST00000585986 SMAD7-006 processed_transcript Homo_sapiens 0 769
ENST00000586093 SMAD7-007 protein_coding Homo_sapiens 0 809
ENST00000587336 SMAD7-004 processed_transcript Homo_sapiens 0 791
ENST00000588190 SMAD7-008 processed_transcript Homo_sapiens 0 440
ENST00000589634 SMAD7-005 protein_coding Homo_sapiens 0 2025
ENST00000591805 SMAD7-002 protein_coding Homo_sapiens 0 1077

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