C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SRY (sex determining region Y)-box 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000173447 Sox8-002 ENSMUSG00000024176 10090 - 17:25568710-25570686 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastColonLiverMuscleOvaryENSMUST00000173447
Transcript ID Adrenal Bladder Breast Colon Liver Muscle Ovary
ENSMUST00000173447 0.463±0.07 0.365±0.00 0.659±0.00 0.300±0.00 0.026±0.01 0.097±0.00 1.385±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000U6 CIL_0000U6_0002 CGP 17:25565892-25662826

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001649 IMP osteoblast differentiation
GO:0001701 IGI in utero embryonic development
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IMP cytoplasm
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007283 IMP spermatogenesis
GO:0007422 IGI peripheral nervous system development
GO:0008584 IGI male gonad development
GO:0010628 IGI positive regulation of gene expression
GO:0010817 IMP regulation of hormone levels
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0035914 IMP skeletal muscle cell differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045165 IGI cell fate commitment
GO:0045444 IMP fat cell differentiation
GO:0045662 IDA negative regulation of myoblast differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046533 IGI negative regulation of photoreceptor cell differentiation
GO:0046982 IDA protein heterodimerization activity
GO:0048469 IGI cell maturation
GO:0048709 IMP oligodendrocyte differentiation
GO:0060009 IGI Sertoli cell development
GO:0060018 IGI astrocyte fate commitment
GO:0060041 IGI retina development in camera-type eye
GO:0060221 IGI retinal rod cell differentiation
GO:0060612 IMP adipose tissue development
GO:0061138 IGI morphogenesis of a branching epithelium
GO:0072197 IGI ureter morphogenesis
GO:0072289 IGI metanephric nephron tubule formation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000325404 SOX2-001 protein_coding Homo_sapiens 0.000000006 68

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