C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hemopoietic cell kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000189688 Hck-201 ENSMUSG00000003283 10090 + 2:153108468-153151439 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008N4 CIL_0008N4_0002 VISTA 2:152517372-153118197
CIL_0004A2 CIL_0004A2_0002 CGP 2:153065955-153151441
CIL_00071A CIL_00071A_0003 CGP 2:153108468-153210466

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004713 ISS protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005764 ISS lysosome
GO:0005794 IEA Golgi apparatus
GO:0005884 ISS actin filament
GO:0006887 IEA exocytosis
GO:0006909 IMP phagocytosis
GO:0006954 IEA inflammatory response
GO:0008284 ISS positive regulation of cell proliferation
GO:0008360 ISS regulation of cell shape
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0030054 IEA cell junction
GO:0031234 ISS extrinsic component of cytoplasmic side of plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0042995 IEA cell projection
GO:0045087 IEA innate immune response
GO:0046777 ISS protein autophosphorylation
GO:0050764 ISS regulation of phagocytosis
GO:0050830 IGI defense response to Gram-positive bacterium
GO:0071801 ISS regulation of podosome assembly
GO:2000251 ISS positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000081536 hck-201 protein_coding Danio_rerio 0 651
ENSDART00000135787 hck-001 protein_coding Danio_rerio 0 651
ENST00000262651 HCK-005 nonsense_mediated_decay Homo_sapiens 0 1664
ENST00000375852 HCK-001 protein_coding Homo_sapiens 0 1744
ENST00000375862 HCK-002 protein_coding Homo_sapiens 0 1757
ENST00000486475 HCK-004 nonsense_mediated_decay Homo_sapiens 0 1668
ENST00000518730 HCK-007 protein_coding Homo_sapiens 0 1757
ENST00000520553 HCK-006 protein_coding Homo_sapiens 0 1744
ENST00000534862 HCK-201 protein_coding Homo_sapiens 0 1744
ENST00000538448 HCK-202 protein_coding Homo_sapiens 0 1668

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