C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hemopoietic cell kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000003283 Hck 10090 + 2:153108468-153151441 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003370 Hck-002 153108468-153151441 protein_coding
  ENSMUST00000109799 Hck-001 153108468-153151441 protein_coding
  ENSMUST00000189688 Hck-201 153108468-153151439 protein_coding
  ENSMUST00000191431 Hck-202 153108468-153151439 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003370ENSMUST00000191431
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003370 3.939±2.04 0.935±0.27 0.697±0.00 0.422±0.00 7.587±2.20 3.515±0.23 0.192±0.10 0.343±0.09 2.694±3.60 15.583±3.27 0.085±0.13 2.634±2.08 0.203±0.16 0.066±0.03
ENSMUST00000191431 N/A 0.937±0.27 1.494±0.13 0.345±0.11 5.471±3.97 4.473±1.42 0.438±0.16 1.301±0.52 3.197±3.10 9.839±7.05 0.086±0.13 1.997±1.02 0.328±0.23 0.066±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008N4 CIL_0008N4_0002 VISTA 2:152517372-153118197
CIL_0004A2 CIL_0004A2_0002 CGP 2:153065955-153151441
CIL_00071A CIL_00071A_0003 CGP 2:153108468-153210466

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004713 IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005764 ISS lysosome
GO:0005794 IEA Golgi apparatus
GO:0005884 ISS actin filament
GO:0006887 IEA exocytosis
GO:0006909 IMP phagocytosis
GO:0006954 IEA inflammatory response
GO:0008284 ISS positive regulation of cell proliferation
GO:0008360 ISS regulation of cell shape
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030054 IEA cell junction
GO:0031234 ISS extrinsic component of cytoplasmic side of plasma membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0042995 IEA cell projection
GO:0045087 IEA innate immune response
GO:0046777 ISS protein autophosphorylation
GO:0050764 ISS regulation of phagocytosis
GO:0050830 IGI defense response to Gram-positive bacterium
GO:0071801 ISS regulation of podosome assembly
GO:2000251 ISS positive regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058647 hck hemopoietic cell kinase protein_coding Danio_rerio
ENSG00000101336 HCK HCK proto-oncogene, Src family tyrosine kinase protein_coding Homo_sapiens

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