C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000189444 NFKB2-001 ENSG00000077150 9606 + 10:102395706-102402524 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000189444
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000189444 5.943±0.00 26.349±0.00 0.468±0.00 1.633±1.39 3.725±1.22 6.983±6.58 1.130±0.90 2.498±2.06 0.985±0.51 21.705±19.44 8.682±8.13 14.707±10.13 10.651±1.66 6.863±2.43

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005WJ CIL_0005WJ_0001 CGP 10:102245532-102402529
CIL_0001HR CIL_0001HR_0002 CGP 10:102394110-102421539

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003713 TAS transcription coactivator activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA:IDA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0032481 TAS positive regulation of type I interferon production
GO:0033257 IDA Bcl3/NF-kappaB2 complex
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0045087 TAS innate immune response
GO:0048511 IEA rhythmic process
GO:0051092 TAS positive regulation of NF-kappaB transcription factor activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000111881 Nfkb2-202 protein_coding Mus_musculus 0 3066
ENSMUST00000073116 Nfkb2-201 protein_coding Mus_musculus 0 3064

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