C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ring-box 1, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000216225 RBX1-001 ENSG00000100387 9606 + 22:40951359-40973309 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216225
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216225 19.593±0.00 32.897±0.00 0.318±0.00 16.365±10.20 23.947±0.00 8.670±7.78 10.911±10.00 14.893±11.29 9.346±6.66 16.961±15.06 7.818±5.04 13.516±8.55 26.904±11.68 20.396±14.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00065L CIL_00065L_0001 CGP 22:40859549-40973309

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005829 ISS cytosol
GO:0006281 IEA DNA repair
GO:0006513 IDA protein monoubiquitination
GO:0007219 TAS Notch signaling pathway
GO:0008270 IEA zinc ion binding
GO:0016032 TAS viral process
GO:0016567 IDA protein ubiquitination
GO:0019005 ISS SCF ubiquitin ligase complex
GO:0019788 IDA NEDD8 ligase activity
GO:0030163 IEA protein catabolic process
GO:0030891 IEA VCB complex
GO:0031146 ISS SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031461 IDA cullin-RING ubiquitin ligase complex
GO:0031462 IDA Cul2-RING ubiquitin ligase complex
GO:0031463 IDA Cul3-RING ubiquitin ligase complex
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 IDA Cul4B-RING E3 ubiquitin ligase complex
GO:0031466 IDA Cul5-RING ubiquitin ligase complex
GO:0031467 IDA Cul7-RING ubiquitin ligase complex
GO:0031625 IDA ubiquitin protein ligase binding
GO:0032403 IEA protein complex binding
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045116 IDA protein neddylation
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 TAS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023036 Rbx1-201 protein_coding Mus_musculus 0 564
ENSMUST00000173786 Gm9840-001 processed_pseudogene Mus_musculus 0 460

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