C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: complement component 1, q subcomponent binding protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000225698 C1QBP-001 ENSG00000108561 9606 - 17:5432777-5439155 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000225698
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000225698 58.381±0.00 11.575±0.00 70.006±11.51 42.663±16.43 50.722±4.68 44.617±20.45 62.852±20.36 36.003±6.98 37.160±12.87 49.762±7.96 56.623±19.56 48.953±11.83 83.936±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00045W CIL_00045W_0001 CGP 17:5360963-5432876
CIL_00060K CIL_00060K_0002 CGP 17:5419641-5448830
CIL_0000DD CIL_0000DD_0001 CGP 17:5432777-5469060

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001849 IDA complement component C1q binding
GO:0003714 IDA transcription corepressor activity
GO:0003729 ISS mRNA binding
GO:0005080 IEA protein kinase C binding
GO:0005515 IPI protein binding
GO:0005540 IDA hyaluronic acid binding
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 IEA mitochondrial matrix
GO:0005829 IDA cytosol
GO:0005886 TAS plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006397 IEA mRNA processing
GO:0006915 IEA apoptotic process
GO:0006955 TAS immune response
GO:0006958 IEA complement activation, classical pathway
GO:0007596 TAS blood coagulation
GO:0007597 TAS blood coagulation, intrinsic pathway
GO:0008134 IDA transcription factor binding
GO:0008380 IEA RNA splicing
GO:0009986 IDA cell surface
GO:0014065 IMP phosphatidylinositol 3-kinase signaling
GO:0016020 IDA membrane
GO:0016032 IEA viral process
GO:0030449 IDA regulation of complement activation
GO:0030984 IDA kininogen binding
GO:0031690 ISS adrenergic receptor binding
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032695 IDA negative regulation of interleukin-12 production
GO:0039534 IDA negative regulation of MDA-5 signaling pathway
GO:0039536 IDA negative regulation of RIG-I signaling pathway
GO:0042256 IMP mature ribosome assembly
GO:0043065 IMP positive regulation of apoptotic process
GO:0045087 IEA innate immune response
GO:0045785 IMP positive regulation of cell adhesion
GO:0048025 IDA negative regulation of mRNA splicing, via spliceosome
GO:0050687 IMP negative regulation of defense response to virus
GO:0051897 IMP positive regulation of protein kinase B signaling
GO:0070131 ISS positive regulation of mitochondrial translation
GO:0090023 IDA positive regulation of neutrophil chemotaxis
GO:0097177 ISS mitochondrial ribosome binding
GO:1900026 IMP positive regulation of substrate adhesion-dependent cell spreading
GO:1901165 IMP positive regulation of trophoblast cell migration
GO:2000510 IMP positive regulation of dendritic cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000078528 C1qbp-001 protein_coding Mus_musculus 0 870
ENSMUST00000155371 C1qbp-002 retained_intron Mus_musculus 0 488

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