C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Spi-1 proto-oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000227163 SPI1-004 ENSG00000066336 9606 - 11:47354913-47378391 protein_coding

Homo sapiens EnsemblGRCh38

Genome
Exciting message
Genes
Structures from Ensembl
Connecting
Transcripts
Structures from Ensembl
Connecting
Powered by Dalliance 0.11.11

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000227163
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000227163 19.456±0.00 17.184±0.00 5.332±0.00 9.405±0.00 0.757±0.00 3.328±0.00 3.746±1.36 1.977±0.00 20.365±16.70 0.545±0.41 2.755±2.08 14.870±8.73 2.414±1.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002LM CIL_0002LM_0002 CGP 11:47354860-47416501

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000980 ISS RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IBA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001047 IDA core promoter binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001085 ISS RNA polymerase II transcription factor binding
GO:0001205 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001944 IEA vasculature development
GO:0002320 IEA lymphoid progenitor cell differentiation
GO:0002573 IEA myeloid leukocyte differentiation
GO:0003677 IEA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003705 ISS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003723 IEA RNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0030098 IEA lymphocyte differentiation
GO:0030218 IEA erythrocyte differentiation
GO:0030225 IEA macrophage differentiation
GO:0030851 IEA granulocyte differentiation
GO:0035019 IEA somatic stem cell maintenance
GO:0043011 IEA myeloid dendritic cell differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0043966 IMP histone H3 acetylation
GO:0044027 IDA hypermethylation of CpG island
GO:0045347 IEA negative regulation of MHC class II biosynthetic process
GO:0045646 IMP regulation of erythrocyte differentiation
GO:0045814 IDA negative regulation of gene expression, epigenetic
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0051525 ISS NFAT protein binding
GO:0060033 IEA anatomical structure regression
GO:0090241 IMP negative regulation of histone H4 acetylation
GO:1902262 IEA apoptotic process involved in patterning of blood vessels

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002180 Spi1-001 protein_coding Mus_musculus 0 1044
ENSDART00000036729 spi1b-201 protein_coding Danio_rerio 0 246
ENSDART00000093279 spi1b-202 protein_coding Danio_rerio 0 246
ENSDART00000126831 spi1b-203 protein_coding Danio_rerio 0 246
ENSMUST00000132741 Spi1-002 protein_coding Mus_musculus 3e-19 100

Loading