C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor subfamily 1, group D, member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000246672 NR1D1-001 ENSG00000126368 9606 - 17:40092787-40100725 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000246672
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000246672 41.456±0.00 19.015±0.00 44.240±0.00 21.683±0.00 19.771±18.97 8.992±0.00 3.783±2.55 1.152±0.06 18.062±16.87 32.105±29.21 23.992±9.62 8.098±0.94 19.063±12.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0001 VISTA 17:39768583-40372873
CIL_0002KL CIL_0002KL_0001 CGP 17:40019097-40093867
CIL_0002L8 CIL_0002L8_0001 CGP 17:40058290-40100725
CIL_0002GG CIL_0002GG_0001 CGP 17:40092787-40136916

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000978 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001046 IDA core promoter sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001222 IDA transcription corepressor binding
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003714 TAS transcription corepressor activity
GO:0004879 TAS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005978 ISS glycogen biosynthetic process
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007623 IEA circadian rhythm
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0010498 ISS proteasomal protein catabolic process
GO:0010871 IMP negative regulation of receptor biosynthetic process
GO:0019216 ISS regulation of lipid metabolic process
GO:0020037 IDA heme binding
GO:0030154 IEA cell differentiation
GO:0030425 ISS dendrite
GO:0030522 TAS intracellular receptor signaling pathway
GO:0032922 ISS circadian regulation of gene expression
GO:0034144 IMP negative regulation of toll-like receptor 4 signaling pathway
GO:0035947 IMP regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter
GO:0042752 ISS regulation of circadian rhythm
GO:0043197 ISS dendritic spine
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044321 ISS response to leptin
GO:0045598 ISS regulation of fat cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0060086 ISS circadian temperature homeostasis
GO:0061178 ISS regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0061469 ISS regulation of type B pancreatic cell proliferation
GO:0070859 ISS positive regulation of bile acid biosynthetic process
GO:0071222 IMP cellular response to lipopolysaccharide
GO:2000188 ISS regulation of cholesterol homeostasis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000064941 Nr1d1-001 protein_coding Mus_musculus 0 3478
ENSMUST00000139220 Nr1d1-002 processed_transcript Mus_musculus 0 497
ENSMUST00000064187 Thra-001 protein_coding Mus_musculus 0 486
ENSDART00000040468 nr1d1-201 protein_coding Danio_rerio 0 285
ENSDART00000126282 nr1d1-001 protein_coding Danio_rerio 0 285
ENSMUST00000124072 Thra-004 protein_coding Mus_musculus 0 239

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