C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: thyroid hormone receptor alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000064187 Thra-001 ENSMUSG00000058756 10090 + 11:98741811-98769006 protein_coding

Mus musculus EnsemblGRCm38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064187
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064187 43.671±1.88 53.175±9.33 31.403±2.25 184.638±27.30 47.251±4.62 36.750±2.72 30.815±2.43 38.152±3.80 6.875±1.34 63.587±9.25 18.154±3.25 48.048±18.71 5.501±3.71 4.633±0.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098Y CIL_00098Y_0002 VISTA 11:98447152-99051430
CIL_0002KL CIL_0002KL_0002 CGP 11:98704591-98769006
CIL_0002L8 CIL_0002L8_0002 CGP 11:98740638-98775333

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001502 IMP cartilage condensation
GO:0001503 IMP ossification
GO:0002153 IDA steroid receptor RNA activator RNA binding
GO:0002155 IMP regulation of thyroid hormone mediated signaling pathway
GO:0003707 IEA steroid hormone receptor activity
GO:0003727 IDA single-stranded RNA binding
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004887 TAS:ISS thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0007611 IMP learning or memory
GO:0008016 IMP regulation of heart contraction
GO:0008050 IMP female courtship behavior
GO:0008270 IEA zinc ion binding
GO:0009409 IMP response to cold
GO:0009887 IMP organ morphogenesis
GO:0010831 IDA positive regulation of myotube differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030522 IDA:IEA intracellular receptor signaling pathway
GO:0030878 IGI thyroid gland development
GO:0031490 IDA chromatin DNA binding
GO:0032403 IDA protein complex binding
GO:0033032 IMP regulation of myeloid cell apoptotic process
GO:0042994 IDA cytoplasmic sequestering of transcription factor
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045925 IMP positive regulation of female receptivity
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050994 IMP regulation of lipid catabolic process
GO:0060509 IGI Type I pneumocyte differentiation
GO:0070324 ISO:ISS thyroid hormone binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000000160 thraa-001 protein_coding Danio_rerio 0 717
ENSDART00000151127 thraa-002 protein_coding Danio_rerio 0 717
ENSDART00000151575 thraa-003 retained_intron Danio_rerio 0 394
ENST00000246672 NR1D1-001 protein_coding Homo_sapiens 0 486
ENST00000264637 THRA-001 protein_coding Homo_sapiens 0 3415
ENST00000394121 THRA-003 protein_coding Homo_sapiens 0 2780
ENST00000450525 THRA-002 protein_coding Homo_sapiens 0 2375
ENST00000546243 THRA-006 protein_coding Homo_sapiens 0 2076
ENST00000577288 THRA-007 protein_coding Homo_sapiens 0 472
ENST00000577486 THRA-010 protein_coding Homo_sapiens 0 603
ENST00000577637 THRA-011 retained_intron Homo_sapiens 0 525
ENST00000578218 THRA-009 protein_coding Homo_sapiens 0 737
ENST00000584985 THRA-005 protein_coding Homo_sapiens 0 2381
ENST00000585047 THRA-008 protein_coding Homo_sapiens 0 676

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