C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000249071 RAC2-001 ENSG00000128340 9606 - 22:37225261-37244270 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000249071
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000249071 9.663±0.00 101.928±0.00 0.307±0.00 1.031±0.99 7.477±0.00 2.532±0.18 1.604±1.52 3.409±0.00 2.425±1.72 33.498±30.03 0.600±0.55 10.226±5.24 13.262±6.22 2.443±1.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036V CIL_00036V_0001 CGP 22:37204238-37244448
CIL_000486 CIL_000486_0001 CGP 22:37225261-37315345

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005525 IEA:IMP GTP binding
GO:0005622 IEA intracellular
GO:0005635 IEA nuclear envelope
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0005884 IDA actin filament
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006184 IEA GTP catabolic process
GO:0006886 IEA intracellular protein transport
GO:0006913 IEA nucleocytoplasmic transport
GO:0006935 IEA chemotaxis
GO:0007015 IMP actin filament organization
GO:0007165 TAS:IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007264 IEA:TAS small GTPase mediated signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008284 IEA positive regulation of cell proliferation
GO:0010310 TAS regulation of hydrogen peroxide metabolic process
GO:0010592 IMP positive regulation of lamellipodium assembly
GO:0010810 IMP regulation of cell-substrate adhesion
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0030027 IDA lamellipodium
GO:0030031 IEA cell projection assembly
GO:0030036 IEA actin cytoskeleton organization
GO:0030168 TAS platelet activation
GO:0045453 IEA bone resorption
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0060263 IDA regulation of respiratory burst
GO:0070062 IDA extracellular vesicular exosome
GO:0071593 IMP lymphocyte aggregation
GO:0090023 IMP positive regulation of neutrophil chemotaxis
GO:1902622 IMP regulation of neutrophil migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000043214 Rac2-201 protein_coding Mus_musculus 0 771
ENSMUST00000080537 Rac1-001 protein_coding Mus_musculus 0 438
ENSMUST00000100489 Rac1-002 protein_coding Mus_musculus 0 211

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