C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: RAS-related C3 botulinum substrate 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000080537 Rac1-001 ENSMUSG00000001847 10090 - 5:143505478-143528036 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000080537
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000080537 145.937±26.67 135.647±2.13 120.123±2.98 59.890±23.31 95.607±43.41 279.093±54.26 76.724±2.63 107.455±19.17 55.088±11.90 153.529±16.06 27.256±4.39 205.865±89.15 64.415±37.44 11.749±5.32

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0001891 IDA phagocytic cup
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0002093 IMP auditory receptor cell morphogenesis
GO:0002551 IEA mast cell chemotaxis
GO:0003382 IMP epithelial cell morphogenesis
GO:0003924 IDA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IDA GTP binding
GO:0005737 IDA cytoplasm
GO:0005802 IEA trans-Golgi network
GO:0005829 ISS cytosol
GO:0005884 IEA actin filament
GO:0005925 IEA focal adhesion
GO:0006897 IDA endocytosis
GO:0006911 IMP phagocytosis, engulfment
GO:0006928 IEA cellular component movement
GO:0006935 IEA chemotaxis
GO:0006972 IDA hyperosmotic response
GO:0007010 IDA cytoskeleton organization
GO:0007015 IEA actin filament organization
GO:0007155 IDA cell adhesion
GO:0007186 IGI G-protein coupled receptor signaling pathway
GO:0007264 IDA small GTPase mediated signal transduction
GO:0007411 IMP axon guidance
GO:0008283 IEA cell proliferation
GO:0010592 ISO positive regulation of lamellipodium assembly
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0016020 IDA membrane
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016358 IDA dendrite development
GO:0016477 IDA cell migration
GO:0017137 IEA Rab GTPase binding
GO:0019897 IDA extrinsic component of plasma membrane
GO:0019899 IEA enzyme binding
GO:0019901 IEA protein kinase binding
GO:0021799 IMP cerebral cortex radially oriented cell migration
GO:0021831 IMP embryonic olfactory bulb interneuron precursor migration
GO:0030027 IDA lamellipodium
GO:0030032 TAS lamellipodium assembly
GO:0030036 IEA actin cytoskeleton organization
GO:0030041 IDA actin filament polymerization
GO:0030334 IMP regulation of cell migration
GO:0030742 IPI GTP-dependent protein binding
GO:0030838 IDA positive regulation of actin filament polymerization
GO:0031410 IEA cytoplasmic vesicle
GO:0031529 ISO ruffle organization
GO:0031996 IEA thioesterase binding
GO:0032587 IDA ruffle membrane
GO:0032707 IEA negative regulation of interleukin-23 production
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0036464 IEA cytoplasmic ribonucleoprotein granule
GO:0042995 IDA cell projection
GO:0043552 IMP positive regulation of phosphatidylinositol 3-kinase activity
GO:0043652 IDA engulfment of apoptotic cell
GO:0045216 IMP cell-cell junction organization
GO:0045453 IEA bone resorption
GO:0045740 IEA positive regulation of DNA replication
GO:0048532 IMP anatomical structure arrangement
GO:0048813 IGI dendrite morphogenesis
GO:0048870 ISS cell motility
GO:0051022 ISS Rho GDP-dissociation inhibitor binding
GO:0051496 IEA positive regulation of stress fiber assembly
GO:0051668 IEA localization within membrane
GO:0051894 IEA positive regulation of focal adhesion assembly
GO:0060071 IGI Wnt signaling pathway, planar cell polarity pathway
GO:0060263 IEA regulation of respiratory burst
GO:0070062 IEA extracellular vesicular exosome
GO:0071526 ISS semaphorin-plexin signaling pathway
GO:0071542 IGI dopaminergic neuron differentiation
GO:0072659 IDA protein localization to plasma membrane
GO:0090023 IMP positive regulation of neutrophil chemotaxis
GO:0090103 IMP cochlea morphogenesis
GO:0097178 IMP ruffle assembly
GO:1900026 IEA positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000130877 rac1b-001 protein_coding Danio_rerio 0 555
ENSDART00000047206 rac1b-201 protein_coding Danio_rerio 0 555
ENSDART00000135818 RAC1 (6 of 8)-202 protein_coding Danio_rerio 0 438
ENSDART00000141964 RAC1 (6 of 8)-201 protein_coding Danio_rerio 0 333
ENSDART00000022562 rhogb-001 protein_coding Danio_rerio 4e-25 121
ENSDART00000099388 rhoga-201 protein_coding Danio_rerio 4e-20 104
ENSDART00000152363 rhoga-001 protein_coding Danio_rerio 4e-20 104
ENST00000249071 RAC2-001 protein_coding Homo_sapiens 0 438
ENST00000348035 RAC1-001 protein_coding Homo_sapiens 0 1057
ENST00000356142 RAC1-002 protein_coding Homo_sapiens 0 564
ENST00000401529 RAC2-002 protein_coding Homo_sapiens 1e-29 134
ENST00000407987 RP11-207F8.1-001 processed_pseudogene Homo_sapiens 0 267
ENST00000416129 RAC1P3-001 processed_pseudogene Homo_sapiens 0 492
ENST00000419413 RAC1P4-001 processed_pseudogene Homo_sapiens 0 704
ENST00000441619 RAC2-003 protein_coding Homo_sapiens 0 422
ENST00000469532 RAC2-006 retained_intron Homo_sapiens 0 211
ENST00000473564 RAC1-005 retained_intron Homo_sapiens 0 377
ENST00000488373 RAC1-004 processed_transcript Homo_sapiens 0 776
ENST00000495499 RAC1-006 retained_intron Homo_sapiens 0 457
ENST00000497741 RAC1-003 processed_transcript Homo_sapiens 0 723
ENST00000511164 RAC1P2-001 processed_pseudogene Homo_sapiens 0 782
ENST00000512182 RAC1P5-001 processed_pseudogene Homo_sapiens 0 673

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