C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein inhibitor of activated STAT, 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000249636 PIAS1-001 ENSG00000033800 9606 + 15:68054179-68193846 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastHeartENST00000249636
Transcript ID Breast Heart
ENST00000249636 2.226±0.00 3.165±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DX CIL_0008DX_0001 VISTA 15:67486945-68088375
CIL_00098T CIL_00098T_0001 VISTA 15:67539824-68142788
CIL_0008FO CIL_0008FO_0001 VISTA 15:67583922-68185582
CIL_0004L4 CIL_0004L4_0002 CGP 15:67819704-68198603

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003713 NAS transcription coactivator activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007259 TAS JAK-STAT cascade
GO:0007283 IEA spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016605 ISS PML body
GO:0016925 ISS protein sumoylation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019789 IDA SUMO ligase activity
GO:0019899 IPI enzyme binding
GO:0019904 IEA protein domain specific binding
GO:0030521 NAS androgen receptor signaling pathway
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032436 ISS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033235 IDA positive regulation of protein sumoylation
GO:0042127 ISS regulation of cell proliferation
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0050681 NAS androgen receptor binding
GO:0051152 IEA positive regulation of smooth muscle cell differentiation
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060334 TAS regulation of interferon-gamma-mediated signaling pathway
GO:0065004 IEA protein-DNA complex assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098651 Pias1-201 protein_coding Mus_musculus 0 3175
ENSDART00000090310 pias1b-001 protein_coding Danio_rerio 0.000000001 71

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