C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ER degradation enhancer, mannosidase alpha-like 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000256497 EDEM1-001 ENSG00000134109 9606 + 3:5187673-5219957 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000256497
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000256497 5.572±0.00 6.248±0.00 0.897±0.71 6.293±0.00 1.615±0.86 0.971±0.74 6.078±0.00 15.418±0.00 8.350±0.00 1.023±0.78 2.829±2.44 1.942±0.75 2.708±1.47

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005RI CIL_0005RI_0001 CGP 3:5122220-5219957
CIL_0005RO CIL_0005RO_0001 CGP 3:5187646-7741533

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004571 IEA mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006457 TAS protein folding
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0016020 IEA membrane
GO:0018279 TAS protein N-linked glycosylation via asparagine
GO:0030176 ISS integral component of endoplasmic reticulum membrane
GO:0030433 ISS ER-associated ubiquitin-dependent protein catabolic process
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0051787 IDA misfolded protein binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000089162 Edem1-201 protein_coding Mus_musculus 0 2375

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