C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: T-box 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000257566 TBX3-002 ENSG00000135111 9606 - 12:114670255-114683590 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000257566
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000257566 1.608±0.00 2.100±0.00 0.331±0.00 3.333±0.00 1.352±0.00 0.674±0.00 2.630±0.00 0.762±0.00 2.130±0.00 2.317±1.47 7.643±0.95 1.889±1.75

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00095S CIL_00095S_0001 VISTA 12:114119731-114721669
CIL_00092A CIL_00092A_0001 VISTA 12:114147407-114748589
CIL_0008K6 CIL_0008K6_0001 VISTA 12:114385728-114986369
CIL_0008K7 CIL_0008K7_0001 VISTA 12:114386589-114987495

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001085 ISS RNA polymerase II transcription factor binding
GO:0001102 ISS RNA polymerase II activating transcription factor binding
GO:0001501 IMP skeletal system development
GO:0001568 IEA blood vessel development
GO:0001701 IEA in utero embryonic development
GO:0001947 IEA heart looping
GO:0003007 IEA heart morphogenesis
GO:0003151 IEA outflow tract morphogenesis
GO:0003167 IEA atrioventricular bundle cell differentiation
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007569 IDA cell aging
GO:0008284 IDA positive regulation of cell proliferation
GO:0008595 IMP anterior/posterior axis specification, embryo
GO:0009887 IDA organ morphogenesis
GO:0010159 IEA specification of organ position
GO:0019827 IEA stem cell maintenance
GO:0021761 IEA limbic system development
GO:0030539 IMP male genitalia development
GO:0030540 IMP female genitalia development
GO:0030857 IEA negative regulation of epithelial cell differentiation
GO:0030879 IMP mammary gland development
GO:0032275 IMP luteinizing hormone secretion
GO:0035108 IEA limb morphogenesis
GO:0035115 IMP embryonic forelimb morphogenesis
GO:0035136 IDA forelimb morphogenesis
GO:0042127 IEA regulation of cell proliferation
GO:0042733 IMP embryonic digit morphogenesis
GO:0043066 IDA negative regulation of apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0045662 IDA negative regulation of myoblast differentiation
GO:0045787 IDA positive regulation of cell cycle
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0046884 IMP follicle-stimulating hormone secretion
GO:0048332 IMP mesoderm morphogenesis
GO:0055007 IEA cardiac muscle cell differentiation
GO:0060021 IEA palate development
GO:0060412 IEA ventricular septum morphogenesis
GO:0060444 IEA branching involved in mammary gland duct morphogenesis
GO:0060596 IEA mammary placode formation
GO:0060923 IEA cardiac muscle cell fate commitment
GO:0060931 IEA sinoatrial node cell development
GO:0090398 IDA cellular senescence
GO:2000648 IEA positive regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018748 Tbx3-001 protein_coding Mus_musculus 0 2392
ENSMUST00000079719 Tbx3-201 protein_coding Mus_musculus 0 1406
ENSMUST00000121021 Tbx3-002 protein_coding Mus_musculus 0 1406
ENSMUST00000018407 Tbx5-201 protein_coding Mus_musculus 0.0000001 64

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