C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: T-box 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018748 Tbx3-001 ENSMUSG00000018604 10090 + 5:119671018-119684724 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018748
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018748 1.862±1.35 66.346±2.15 5.464±1.04 0.061±0.00 3.623±1.99 1.795±0.70 0.603±0.14 0.700±0.10 1.929±1.63 7.618±1.70 0.719±0.03 7.121±3.03 1.500±0.47 0.233±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008K7 CIL_0008K7_0002 VISTA 5:119367993-119968855
CIL_0008K6 CIL_0008K6_0002 VISTA 5:119368986-119969581
CIL_00092A CIL_00092A_0002 VISTA 5:119496787-120097947
CIL_00095S CIL_00095S_0002 VISTA 5:119521983-120124240
CIL_0004YZ CIL_0004YZ_0002 CGP 5:119670669-119885218

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001501 ISS skeletal system development
GO:0001568 IMP blood vessel development
GO:0001701 IMP in utero embryonic development
GO:0001947 IMP heart looping
GO:0003007 IMP heart morphogenesis
GO:0003151 IMP outflow tract morphogenesis
GO:0003167 IMP atrioventricular bundle cell differentiation
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007569 IDA cell aging
GO:0008284 ISS positive regulation of cell proliferation
GO:0008595 ISS anterior/posterior axis specification, embryo
GO:0009887 ISO organ morphogenesis
GO:0010159 IDA specification of organ position
GO:0019827 IMP stem cell maintenance
GO:0021761 IMP limbic system development
GO:0030539 ISS male genitalia development
GO:0030540 ISS female genitalia development
GO:0030857 IMP negative regulation of epithelial cell differentiation
GO:0030879 IMP mammary gland development
GO:0032275 ISS luteinizing hormone secretion
GO:0035108 IMP limb morphogenesis
GO:0035115 ISS embryonic forelimb morphogenesis
GO:0035136 ISO forelimb morphogenesis
GO:0042127 IMP regulation of cell proliferation
GO:0042733 ISS embryonic digit morphogenesis
GO:0043066 ISS negative regulation of apoptotic process
GO:0043565 ISS sequence-specific DNA binding
GO:0045662 ISS negative regulation of myoblast differentiation
GO:0045787 ISS positive regulation of cell cycle
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0046884 ISS follicle-stimulating hormone secretion
GO:0048332 ISS mesoderm morphogenesis
GO:0055007 IMP cardiac muscle cell differentiation
GO:0060021 IGI palate development
GO:0060412 IMP ventricular septum morphogenesis
GO:0060444 IMP branching involved in mammary gland duct morphogenesis
GO:0060596 IGI mammary placode formation
GO:0060923 IMP cardiac muscle cell fate commitment
GO:0060931 IMP sinoatrial node cell development
GO:0090398 ISS cellular senescence
GO:2000648 IMP positive regulation of stem cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000006380 tbx3a-001 protein_coding Danio_rerio 0 477
ENST00000257566 TBX3-002 protein_coding Homo_sapiens 0 2392
ENST00000349155 TBX3-001 protein_coding Homo_sapiens 0 1406
ENST00000552054 TBX3-003 retained_intron Homo_sapiens 0 898
ENST00000613550 TBX3-201 protein_coding Homo_sapiens 0 1391

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