C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific methyltransferase 2E
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000257745 KMT2E-201 ENSG00000005483 9606 + 7:105014190-105114084 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000257745
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000257745 9.591±0.00 6.105±0.00 5.062±0.00 7.397±0.00 2.144±0.00 5.617±0.00 1.456±0.00 4.897±0.00 8.721±3.93 3.342±2.25 9.361±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005BG CIL_0005BG_0002 CGP 7:104328656-105114361
CIL_00040Y CIL_00040Y_0001 CGP 7:105014179-105399308

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002446 ISS neutrophil mediated immunity
GO:0003713 IMP transcription coactivator activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006306 ISS DNA methylation
GO:0006351 IEA transcription, DNA-templated
GO:0007050 IEA cell cycle arrest
GO:0008270 IEA zinc ion binding
GO:0019899 IPI enzyme binding
GO:0030218 ISS erythrocyte differentiation
GO:0030854 IMP positive regulation of granulocyte differentiation
GO:0042119 ISS neutrophil activation
GO:0042800 IDA histone methyltransferase activity (H3-K4 specific)
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0048384 IMP retinoic acid receptor signaling pathway
GO:0051568 IDA histone H3-K4 methylation
GO:0070688 IDA MLL5-L complex
GO:0071300 IDA cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000115128 Kmt2e-002 protein_coding Mus_musculus 0 4894
ENSMUST00000094962 Kmt2e-001 protein_coding Mus_musculus 0 4894
ENSMUST00000126586 Kmt2e-004 nonsense_mediated_decay Mus_musculus 0 935
ENSMUST00000146375 Kmt2e-003 processed_transcript Mus_musculus 0 931
ENSMUST00000088392 Srpk2-201 protein_coding Mus_musculus 0 460
ENSDART00000123369 kmt2e-001 protein_coding Danio_rerio 3e-38 165

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