C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: SKI-like proto-oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000259119 SKIL-011 ENSG00000136603 9606 + 3:170357726-170392748 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartLiverLungMuscleOvaryENST00000259119
Transcript ID Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary
ENST00000259119 1.771±0.00 2.808±0.00 20.317±0.00 4.348±0.00 1.098±0.00 3.945±0.00 8.331±0.00 1.765±0.00 10.764±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XK CIL_0002XK_0001 CGP 3:170222365-170396835
CIL_0002Z6 CIL_0002Z6_0001 CGP 3:170357678-170860380

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 ISS chromatin binding
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007050 ISS cell cycle arrest
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007519 IDA skeletal muscle tissue development
GO:0010467 TAS gene expression
GO:0016605 IDA PML body
GO:0019904 IPI protein domain specific binding
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032403 IDA protein complex binding
GO:0042981 ISS regulation of apoptotic process
GO:0043234 IDA protein complex
GO:0045596 ISS negative regulation of cell differentiation
GO:0046332 IEA SMAD binding
GO:0046677 IEP response to antibiotic
GO:0050772 IMP positive regulation of axonogenesis
GO:0070207 IDA protein homotrimerization
GO:0070208 IDA protein heterotrimerization
GO:0070848 IDA response to growth factor

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000029194 Skil-201 protein_coding Mus_musculus 0 2170
ENSMUST00000118204 Skil-002 protein_coding Mus_musculus 0 2170
ENSMUST00000118470 Skil-001 protein_coding Mus_musculus 0 1493
ENSMUST00000144756 Skil-004 retained_intron Mus_musculus 0 1264
ENSMUST00000117728 Skil-003 protein_coding Mus_musculus 0 1164
ENSMUST00000123532 Skil-005 protein_coding Mus_musculus 0 584

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