C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATP-binding cassette, sub-family G (WHITE), member 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000260645 ABCG5-001 ENSG00000138075 9606 - 2:43812472-43838819 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyOvaryTestisENST00000260645
Transcript ID Brain Kidney Ovary Testis
ENST00000260645 0.067±0.05 4.304±0.00 0.019±0.00 0.037±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XP CIL_0001XP_0001 CGP 2:43774039-43838865
CIL_0001XO CIL_0001XO_0001 CGP 2:43812472-43878466

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0007584 IEA response to nutrient
GO:0007588 IGI excretion
GO:0010212 IEA response to ionizing radiation
GO:0010949 IMP negative regulation of intestinal phytosterol absorption
GO:0015918 TAS sterol transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IMP apical plasma membrane
GO:0016887 IDA:IEA ATPase activity
GO:0017127 IGI cholesterol transporter activity
GO:0030299 IC intestinal cholesterol absorption
GO:0033344 IGI cholesterol efflux
GO:0042493 IEA response to drug
GO:0042632 IMP cholesterol homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0045177 IEA apical part of cell
GO:0045796 IMP negative regulation of intestinal cholesterol absorption
GO:0046982 IPI protein heterodimerization activity
GO:0055085 TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000066175 Abcg5-001 protein_coding Mus_musculus 0 1646
ENSMUST00000163375 Abcg5-002 protein_coding Mus_musculus 0 904

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