C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: HECT and RLD domain containing E3 ubiquitin protein ligase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000261609 HERC2-001 ENSG00000128731 9606 - 15:28111040-28322152 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261609
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261609 1.266±0.00 1.360±0.00 3.283±0.00 2.256±0.14 2.079±1.04 1.149±0.10 2.905±1.61 0.932±0.03 1.765±1.39 1.529±1.06 1.518±0.00 2.143±1.12 0.827±0.21 2.095±1.02

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 IDA:IEA ubiquitin-protein transferase activity
GO:0005085 NAS guanyl-nucleotide exchange factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005743 IEA mitochondrial inner membrane
GO:0005856 IEA cytoskeleton
GO:0006281 IDA DNA repair
GO:0006886 NAS intracellular protein transport
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007283 IEA spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016020 IDA membrane
GO:0016567 IDA:IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0020037 IEA heme binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032183 IDA SUMO binding
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043547 NAS positive regulation of GTPase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000164095 Herc2-202 protein_coding Mus_musculus 0 16640
ENSMUST00000076226 Herc2-201 protein_coding Mus_musculus 0 16640
ENSDART00000110770 herc2-201 protein_coding Danio_rerio 0 2608

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