C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000076226 Herc2-201 ENSMUSG00000030451 10090 + 7:56050155-56231794 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076226
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076226 2.598±1.13 2.138±0.96 6.296±1.16 6.309±1.80 2.337±1.04 1.481±0.65 1.937±0.29 2.190±0.71 1.600±1.00 4.339±1.15 4.461±1.23 4.502±1.98 3.921±1.50 4.401±1.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000391 CIL_000391_0002 CGP 7:55977567-56231794
CIL_0006LG CIL_0006LG_0002 CGP 7:56050155-56536517

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005743 IDA mitochondrial inner membrane
GO:0005856 IEA cytoskeleton
GO:0006281 ISS DNA repair
GO:0006974 ISS cellular response to DNA damage stimulus
GO:0007283 IMP spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016020 IEA membrane
GO:0016567 ISS protein ubiquitination
GO:0016874 IEA ligase activity
GO:0020037 IEA heme binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032183 ISS SUMO binding
GO:0042787 IBA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000110770 herc2-201 protein_coding Danio_rerio 0 4518
ENST00000261609 HERC2-001 protein_coding Homo_sapiens 0 16640
ENST00000424611 HERC2P3-004 retained_intron Homo_sapiens 0 1016
ENST00000426501 HERC2P3-006 processed_transcript Homo_sapiens 0 1114
ENST00000428453 HERC2P3-014 processed_transcript Homo_sapiens 0 2712
ENST00000429257 HERC2P3-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 2712
ENST00000430598 HERC2P3-003 processed_transcript Homo_sapiens 0 2712
ENST00000437318 HERC2P3-005 processed_transcript Homo_sapiens 0 1823
ENST00000440441 HERC2P3-011 processed_transcript Homo_sapiens 0 603
ENST00000440774 HERC2P3-012 processed_transcript Homo_sapiens 0 440
ENST00000456027 HERC2P3-009 retained_intron Homo_sapiens 0 512
ENST00000524476 HERC2P9-005 retained_intron Homo_sapiens 0 931
ENST00000528584 HERC2P9-002 processed_transcript Homo_sapiens 0 1454
ENST00000529353 HERC2P9-006 processed_transcript Homo_sapiens 0 1504
ENST00000529624 HERC2P9-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 4935
ENST00000530420 HERC2P9-003 retained_intron Homo_sapiens 0 1594
ENST00000531834 RP11-578F21.2-001 unprocessed_pseudogene Homo_sapiens 0 604
ENST00000554836 RP11-467L19.8-001 unprocessed_pseudogene Homo_sapiens 0 793
ENST00000559033 HERC2P7-001 unprocessed_pseudogene Homo_sapiens 0 795
ENST00000562229 HERC2P8-002 processed_transcript Homo_sapiens 0 353
ENST00000562687 HERC2P5-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 2514
ENST00000562845 HERC2P11-001 unprocessed_pseudogene Homo_sapiens 0 736
ENST00000563670 HERC2-007 retained_intron Homo_sapiens 0 292
ENST00000564334 HERC2P8-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 874
ENST00000564383 HERC2-009 retained_intron Homo_sapiens 0 488
ENST00000564730 HERC2P4-006 processed_transcript Homo_sapiens 0 649
ENST00000564734 HERC2-003 nonsense_mediated_decay Homo_sapiens 0 3290
ENST00000566500 RP11-578F21.3-001 unprocessed_pseudogene Homo_sapiens 0 726
ENST00000566591 HERC2P4-005 processed_transcript Homo_sapiens 0 763
ENST00000566635 HERC2-006 retained_intron Homo_sapiens 0 1349
ENST00000566902 HERC2P4-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 1369
ENST00000567073 HERC2P8-004 processed_transcript Homo_sapiens 0 1057
ENST00000567869 HERC2-004 retained_intron Homo_sapiens 0 1605
ENST00000568097 HERC2P4-004 processed_transcript Homo_sapiens 0 265
ENST00000568206 HERC2-005 retained_intron Homo_sapiens 0 322
ENST00000569226 HERC2P9-008 retained_intron Homo_sapiens 0 189
ENST00000569335 HERC2-010 retained_intron Homo_sapiens 0 409
ENST00000569537 RP11-529J17.3-001 unprocessed_pseudogene Homo_sapiens 0 848
ENST00000569679 HERC2P5-003 processed_transcript Homo_sapiens 0 353
ENST00000569697 HERC2P5-004 processed_transcript Homo_sapiens 0 418
ENST00000569772 HERC2-011 protein_coding Homo_sapiens 8e-22 108
ENST00000570209 HERC2P10-001 unprocessed_pseudogene Homo_sapiens 0 983
ENST00000612625 RP11-536P16.2-001 unprocessed_pseudogene Homo_sapiens 0 795
ENST00000613386 HERC2P2-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 4771
ENST00000614571 HERC2P2-003 processed_transcript Homo_sapiens 0 241
ENST00000619021 HERC2P2-002 processed_transcript Homo_sapiens 0 4521
ENST00000619355 HERC2P2-001 unprocessed_pseudogene Homo_sapiens 0 285
ENST00000620983 AC243653.1-201 protein_coding Homo_sapiens 0 1349

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