C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cadherin 1, type 1, E-cadherin (epithelial)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000261769 CDH1-001 ENSG00000039068 9606 + 16:68737225-68835548 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000261769
Transcript ID Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000261769 3.124±0.00 0.679±0.00 6.346±1.29 22.879±0.00 12.166±1.55 4.628±0.05 6.176±2.22 7.563±3.67 33.338±1.46 0.843±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004Y9 CIL_0004Y9_0003 CGP 16:68636189-68835548
CIL_0004RG CIL_0004RG_0001 CGP 16:68737225-69085180

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0001829 IEA trophectodermal cell differentiation
GO:0001948 IPI glycoprotein binding
GO:0003382 IEA epithelial cell morphogenesis
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005802 IMP trans-Golgi network
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005912 IEA adherens junction
GO:0005913 IDA cell-cell adherens junction
GO:0005925 IDA focal adhesion
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0007156 NAS:IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007416 IEA synapse assembly
GO:0007605 IEA sensory perception of sound
GO:0008013 IDA beta-catenin binding
GO:0009636 IEA response to toxic substance
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0009986 IEA cell surface
GO:0010033 IEA response to organic substance
GO:0015629 IDA actin cytoskeleton
GO:0016020 IEA membrane
GO:0016021 IDA integral component of membrane
GO:0016235 IDA aggresome
GO:0016323 IEA basolateral plasma membrane
GO:0016328 IDA lateral plasma membrane
GO:0016337 IDA single organismal cell-cell adhesion
GO:0016339 IEA calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016342 IDA catenin complex
GO:0019538 IEA protein metabolic process
GO:0019903 IEA protein phosphatase binding
GO:0019904 IEA protein domain specific binding
GO:0021983 IEA pituitary gland development
GO:0022408 IMP negative regulation of cell-cell adhesion
GO:0022617 TAS extracellular matrix disassembly
GO:0030054 TAS cell junction
GO:0030198 TAS extracellular matrix organization
GO:0030424 IEA axon
GO:0030506 IPI ankyrin binding
GO:0031175 IEA neuron projection development
GO:0032794 IPI GTPase activating protein binding
GO:0032880 IEA regulation of protein localization
GO:0033268 IEA node of Ranvier
GO:0033561 IEA regulation of water loss via skin
GO:0034329 TAS cell junction assembly
GO:0034332 IMP adherens junction organization
GO:0042493 IEA response to drug
GO:0042993 IDA positive regulation of transcription factor import into nucleus
GO:0043219 IEA lateral loop
GO:0043220 IEA Schmidt-Lanterman incisure
GO:0043281 IEA regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043296 IDA apical junction complex
GO:0043679 IEA axon terminus
GO:0045177 IEA apical part of cell
GO:0045216 TAS cell-cell junction organization
GO:0045295 IPI gamma-catenin binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0050776 TAS regulation of immune response
GO:0050839 NAS cell adhesion molecule binding
GO:0051260 IEA protein homooligomerization
GO:0060576 IEA intestinal epithelial cell development
GO:0060662 IEA salivary gland cavitation
GO:0060693 IEA regulation of branching involved in salivary gland morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0070830 IEA tight junction assembly
GO:0071230 IEA cellular response to amino acid stimulus
GO:0071285 IDA cellular response to lithium ion
GO:0071681 IDA cellular response to indole-3-methanol
GO:0071944 IEA cell periphery
GO:0072659 IDA protein localization to plasma membrane
GO:0090002 IMP establishment of protein localization to plasma membrane
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:0090102 IEA cochlea development
GO:2000008 IEA regulation of protein localization to cell surface
GO:2001222 IEA regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000167688 Cdh1-201 protein_coding Mus_musculus 0 1965
ENSMUST00000000312 Cdh1-001 protein_coding Mus_musculus 0 1965

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