C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: amyloid beta (A4) precursor-like protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263574 APLP2-005 ENSG00000084234 9606 + 11:130069906-130144811 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000263574
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000263574 42.843±0.00 24.498±0.00 18.409±0.00 46.842±12.35 31.280±14.83 18.507±0.00 8.737±0.00 35.773±4.19 19.078±1.85 36.982±3.51 6.882±0.00 22.793±1.05 36.440±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000511 CIL_000511_0002 CGP 11:129899706-130144811
CIL_000510 CIL_000510_0002 CGP 11:130069837-130210376

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001967 IEA suckling behavior
GO:0003677 NAS DNA binding
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005886 IEA plasma membrane
GO:0006878 IEA cellular copper ion homeostasis
GO:0007176 IEA regulation of epidermal growth factor-activated receptor activity
GO:0007186 NAS G-protein coupled receptor signaling pathway
GO:0007617 IEA mating behavior
GO:0007626 IEA locomotory behavior
GO:0008201 IEA heparin binding
GO:0008203 IEA cholesterol metabolic process
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0016020 IDA membrane
GO:0016021 NAS integral component of membrane
GO:0030198 IEA extracellular matrix organization
GO:0030900 IEA forebrain development
GO:0030901 IEA midbrain development
GO:0042802 IPI identical protein binding
GO:0043393 IEA regulation of protein binding
GO:0046914 IEA transition metal ion binding
GO:0050885 IEA neuromuscular process controlling balance
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000072634 Aplp2-201 protein_coding Mus_musculus 0 2294
ENSMUST00000079758 Aplp2-202 protein_coding Mus_musculus 0 1801
ENSDART00000077125 aplp2-001 protein_coding Danio_rerio 0 545

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