C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: elastase, neutrophil expressed
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263621 ELANE-201 ENSG00000197561 9606 + 19:852291-856242 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonLiverLungMuscleOvaryPlacentaTestisENST00000263621
Transcript ID Adipose Adrenal Brain Breast Colon Liver Lung Muscle Ovary Placenta Testis
ENST00000263621 34.951±0.00 0.480±0.00 0.277±0.19 0.916±0.00 0.495±0.00 0.852±0.00 49.734±0.00 0.087±0.00 0.412±0.00 0.869±0.96 0.471±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_0000HZ CIL_0000HZ_0001 CGP 19:840960-856247
CIL_000316 CIL_000316_0001 CGP 19:851014-863630

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IMP RNA polymerase II transcription corepressor activity
GO:0002020 IPI protease binding
GO:0003824 IEA catalytic activity
GO:0004175 IDA endopeptidase activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005737 IDA cytoplasm
GO:0006508 IDA:IEA proteolysis
GO:0006874 NAS cellular calcium ion homeostasis
GO:0008201 IDA heparin binding
GO:0008233 IDA peptidase activity
GO:0009411 IDA response to UV
GO:0009986 IDA cell surface
GO:0017053 IDA transcriptional repressor complex
GO:0019955 IPI cytokine binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030141 IDA secretory granule
GO:0030163 NAS protein catabolic process
GO:0030198 TAS extracellular matrix organization
GO:0030574 TAS collagen catabolic process
GO:0042742 IDA defense response to bacterium
GO:0043406 NAS positive regulation of MAP kinase activity
GO:0045079 IDA negative regulation of chemokine biosynthetic process
GO:0045415 IDA negative regulation of interleukin-8 biosynthetic process
GO:0045416 IDA positive regulation of interleukin-8 biosynthetic process
GO:0048661 IDA positive regulation of smooth muscle cell proliferation
GO:0050728 NAS negative regulation of inflammatory response
GO:0050922 NAS negative regulation of chemotaxis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000046091 Elane-201 protein_coding Mus_musculus 0 344

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