C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: superoxide dismutase 1, soluble
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000270142 SOD1-001 ENSG00000142168 9606 + 21:31659622-31668931 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000270142
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000270142 94.079±0.00 87.421±0.00 27.326±0.00 196.724±17.26 60.454±20.15 110.535±63.32 36.117±9.41 242.435±91.16 163.843±121.70 51.321±18.42 59.996±8.86 135.108±54.26 152.616±24.83 120.316±25.73

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000MO CIL_0000MO_0002 CGP 21:31118416-31668931
CIL_0000MH CIL_0000MH_0002 CGP 21:31659622-31732075

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 ISS activation of MAPK activity
GO:0000302 IEA response to reactive oxygen species
GO:0000303 IDA response to superoxide
GO:0001541 ISS ovarian follicle development
GO:0001819 IDA positive regulation of cytokine production
GO:0001890 NAS placenta development
GO:0001895 ISS retina homeostasis
GO:0001975 IEA response to amphetamine
GO:0002262 ISS myeloid cell homeostasis
GO:0002576 TAS platelet degranulation
GO:0004784 IDA superoxide dismutase activity
GO:0005507 IDA copper ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005758 TAS mitochondrial intermembrane space
GO:0005759 NAS mitochondrial matrix
GO:0005777 ISS peroxisome
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006749 ISS glutathione metabolic process
GO:0006801 ISS:IEA superoxide metabolic process
GO:0006879 ISS cellular iron ion homeostasis
GO:0006979 IEA response to oxidative stress
GO:0007283 ISS spermatogenesis
GO:0007566 ISS embryo implantation
GO:0007568 IEA aging
GO:0007569 IMP cell aging
GO:0007596 TAS blood coagulation
GO:0007605 ISS sensory perception of sound
GO:0007626 ISS locomotory behavior
GO:0008089 ISS anterograde axon cargo transport
GO:0008090 ISS retrograde axon cargo transport
GO:0008217 ISS regulation of blood pressure
GO:0008219 IEA cell death
GO:0008270 IDA zinc ion binding
GO:0009408 ISS response to heat
GO:0010033 IDA response to organic substance
GO:0019226 ISS transmission of nerve impulse
GO:0019430 ISS removal of superoxide radicals
GO:0019899 IEA enzyme binding
GO:0030141 IEA secretory granule
GO:0030168 TAS platelet activation
GO:0030346 IDA protein phosphatase 2B binding
GO:0031012 IDA extracellular matrix
GO:0031045 IEA dense core granule
GO:0031410 IDA cytoplasmic vesicle
GO:0031667 IEA response to nutrient levels
GO:0032287 ISS peripheral nervous system myelin maintenance
GO:0032314 IDA regulation of Rac GTPase activity
GO:0032839 IDA dendrite cytoplasm
GO:0032930 IDA positive regulation of superoxide anion generation
GO:0033081 NAS regulation of T cell differentiation in thymus
GO:0034465 IEA response to carbon monoxide
GO:0034599 IEA cellular response to oxidative stress
GO:0035865 IEA cellular response to potassium ion
GO:0040014 ISS regulation of multicellular organism growth
GO:0042493 ISS response to drug
GO:0042542 ISS response to hydrogen peroxide
GO:0042554 IEA superoxide anion generation
GO:0042802 IPI identical protein binding
GO:0042803 NAS protein homodimerization activity
GO:0043005 IEA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043065 IC positive regulation of apoptotic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043085 IDA positive regulation of catalytic activity
GO:0043234 IDA protein complex
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0045471 ISS response to ethanol
GO:0045541 IDA negative regulation of cholesterol biosynthetic process
GO:0045859 IDA regulation of protein kinase activity
GO:0046620 NAS regulation of organ growth
GO:0046677 IEA response to antibiotic
GO:0046688 IEA response to copper ion
GO:0046716 ISS muscle cell cellular homeostasis
GO:0046872 IEA metal ion binding
GO:0048365 IDA Rac GTPase binding
GO:0048538 NAS thymus development
GO:0048678 ISS response to axon injury
GO:0050665 ISS hydrogen peroxide biosynthetic process
GO:0051087 IPI chaperone binding
GO:0051881 IMP regulation of mitochondrial membrane potential
GO:0055114 IEA oxidation-reduction process
GO:0060047 IDA heart contraction
GO:0060052 ISS neurofilament cytoskeleton organization
GO:0060087 ISS relaxation of vascular smooth muscle
GO:0060088 ISS auditory receptor cell stereocilium organization
GO:0070062 IDA extracellular vesicular exosome
GO:0071276 IEA cellular response to cadmium ion
GO:0071318 IEA cellular response to ATP
GO:0072593 IDA reactive oxygen species metabolic process
GO:0097332 IEA response to antipsychotic drug
GO:1902177 IMP positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023707 Sod1-201 protein_coding Mus_musculus 0 462
ENSMUST00000120174 Gm8566-001 processed_pseudogene Mus_musculus 0 422

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