C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: superoxide dismutase 1, soluble
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000023707 Sod1-201 ENSMUSG00000022982 10090 + 16:90220742-90226322 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023707
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023707 307.701±37.23 458.905±147.51 583.193±38.70 295.543±105.44 283.570±7.95 194.687±16.98 203.975±13.06 537.295±52.18 826.094±251.42 320.687±25.24 186.820±5.22 408.648±278.85 469.129±121.52 237.608±121.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000MO CIL_0000MO_0003 CGP 16:89787111-90226322
CIL_0000MH CIL_0000MH_0003 CGP 16:90220742-90284425

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0000302 IMP response to reactive oxygen species
GO:0000303 IMP response to superoxide
GO:0001541 IMP ovarian follicle development
GO:0001819 ISS positive regulation of cytokine production
GO:0001895 IMP retina homeostasis
GO:0001975 IEA response to amphetamine
GO:0002262 IGI myeloid cell homeostasis
GO:0004784 IMP superoxide dismutase activity
GO:0005507 ISS copper ion binding
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005615 ISS extracellular space
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005739 ISS mitochondrion
GO:0005758 IEA mitochondrial intermembrane space
GO:0005777 IEA peroxisome
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0006749 IMP glutathione metabolic process
GO:0006801 IMP superoxide metabolic process
GO:0006879 IMP cellular iron ion homeostasis
GO:0006979 IDA response to oxidative stress
GO:0007283 IMP spermatogenesis
GO:0007566 IMP embryo implantation
GO:0007568 IMP aging
GO:0007569 IEA cell aging
GO:0007605 IMP sensory perception of sound
GO:0007626 IMP locomotory behavior
GO:0008089 IMP anterograde axon cargo transport
GO:0008090 IMP retrograde axon cargo transport
GO:0008217 IMP regulation of blood pressure
GO:0008270 ISS zinc ion binding
GO:0009408 IMP response to heat
GO:0010033 ISS response to organic substance
GO:0019226 IMP transmission of nerve impulse
GO:0019430 IMP removal of superoxide radicals
GO:0019899 IEA enzyme binding
GO:0030141 IEA secretory granule
GO:0030346 ISS protein phosphatase 2B binding
GO:0031012 ISS extracellular matrix
GO:0031045 IEA dense core granule
GO:0031410 ISS cytoplasmic vesicle
GO:0031667 IEA response to nutrient levels
GO:0032287 IMP peripheral nervous system myelin maintenance
GO:0032314 IEA regulation of Rac GTPase activity
GO:0032839 ISS dendrite cytoplasm
GO:0032930 IEA positive regulation of superoxide anion generation
GO:0034465 IEA response to carbon monoxide
GO:0034599 IEA cellular response to oxidative stress
GO:0035865 IEA cellular response to potassium ion
GO:0040014 IMP regulation of multicellular organism growth
GO:0042493 IMP response to drug
GO:0042542 IMP response to hydrogen peroxide
GO:0042554 IDA superoxide anion generation
GO:0042802 IEA identical protein binding
GO:0043005 IEA neuron projection
GO:0043025 ISS neuronal cell body
GO:0043066 IDA negative regulation of apoptotic process
GO:0043085 ISS positive regulation of catalytic activity
GO:0043234 ISS protein complex
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045471 IMP response to ethanol
GO:0045541 ISS negative regulation of cholesterol biosynthetic process
GO:0045859 ISS regulation of protein kinase activity
GO:0046677 IEA response to antibiotic
GO:0046688 IEA response to copper ion
GO:0046716 IMP muscle cell cellular homeostasis
GO:0048365 IEA Rac GTPase binding
GO:0048678 IMP response to axon injury
GO:0050665 IMP hydrogen peroxide biosynthetic process
GO:0051087 ISS chaperone binding
GO:0051881 ISS regulation of mitochondrial membrane potential
GO:0055114 IEA oxidation-reduction process
GO:0060047 IMP heart contraction
GO:0060052 IGI neurofilament cytoskeleton organization
GO:0060087 IMP relaxation of vascular smooth muscle
GO:0060088 IMP auditory receptor cell stereocilium organization
GO:0070062 IEA extracellular vesicular exosome
GO:0071276 IEA cellular response to cadmium ion
GO:0071318 IEA cellular response to ATP
GO:0072593 ISS reactive oxygen species metabolic process
GO:0097332 IEA response to antipsychotic drug
GO:1902177 IEA positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000270142 SOD1-001 protein_coding Homo_sapiens 0 462
ENST00000389995 SOD1-002 protein_coding Homo_sapiens 0 396
ENST00000470944 SOD1-003 processed_transcript Homo_sapiens 0 396

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