C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: atypical chemokine receptor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000272928 ACKR3-001 ENSG00000144476 9606 + 2:236569641-236582358 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000272928
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000272928 10.976±0.00 4.465±0.00 0.227±0.00 0.423±0.32 5.226±2.39 4.895±3.72 1.496±0.09 0.879±0.00 2.280±0.65 2.848±1.27 2.584±1.70 1.399±0.80 13.917±1.47 2.070±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Q8 CIL_0008Q8_0001 VISTA 2:236320043-236922418
CIL_0002W2 CIL_0002W2_0001 CGP 2:236324147-236582358
CIL_0007QN CIL_0007QN_0001 VISTA 2:236387535-236989164
CIL_0000XT CIL_0000XT_0001 CGP 2:236567787-237100466

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001570 IEA vasculogenesis
GO:0004930 IEA G-protein coupled receptor activity
GO:0005044 IMP scavenger receptor activity
GO:0005515 IPI protein binding
GO:0005768 IDA endosome
GO:0005886 IDA plasma membrane
GO:0005905 IDA coated pit
GO:0006935 IEA chemotaxis
GO:0007155 IEA cell adhesion
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0009986 IDA cell surface
GO:0015026 IEA coreceptor activity
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0016494 IMP C-X-C chemokine receptor activity
GO:0019958 IMP C-X-C chemokine binding
GO:0031623 IMP receptor internalization
GO:0070098 IMP chemokine-mediated signaling pathway
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:1902230 IMP negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000065587 Ackr3-001 protein_coding Mus_musculus 0 1365

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