C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: telomeric repeat binding factor (NIMA-interacting) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000276602 TERF1-002 ENSG00000147601 9606 + 8:73008864-73048122 protein_coding

Homo sapiens EnsemblGRCh38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000276602
Transcript ID Adrenal Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000276602 2.802±0.00 0.740±0.00 0.896±0.00 1.440±1.08 0.269±0.00 0.408±0.08 1.666±0.15 0.504±0.42 2.358±1.01 2.234±0.45 3.721±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003GB CIL_0003GB_0001 CGP 8:72537391-73048122
CIL_000132 CIL_000132_0001 CGP 8:73008864-73124088

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 IEP G2/M transition of mitotic cell cycle
GO:0000723 TAS:IEA telomere maintenance
GO:0000781 IDA:IEA chromosome, telomeric region
GO:0000783 IDA nuclear telomere cap complex
GO:0001309 IDA age-dependent telomere shortening
GO:0003677 NAS:IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003691 IDA double-stranded telomeric DNA binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0005819 IDA spindle
GO:0005856 IEA cytoskeleton
GO:0007004 NAS telomere maintenance via telomerase
GO:0007067 IEA mitotic nuclear division
GO:0007094 IMP mitotic spindle assembly checkpoint
GO:0008017 IDA microtubule binding
GO:0008156 IDA negative regulation of DNA replication
GO:0008301 IDA DNA binding, bending
GO:0010834 IMP telomere maintenance via telomere shortening
GO:0031116 IDA positive regulation of microtubule polymerization
GO:0032211 IGI negative regulation of telomere maintenance via telomerase
GO:0032214 NAS negative regulation of telomere maintenance via semi-conservative replication
GO:0042162 IDA:IEA telomeric DNA binding
GO:0042803 IPI:IEA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0045840 IMP positive regulation of mitosis
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0046982 IDA protein heterodimerization activity
GO:0051260 IDA protein homooligomerization
GO:0051974 IGI negative regulation of telomerase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000186565 Terf1-004 processed_transcript Mus_musculus 0 669
ENSMUST00000188371 Terf1-001 protein_coding Mus_musculus 0 669
ENSMUST00000188684 Terf1-003 retained_intron Mus_musculus 0 532
ENSMUST00000027057 Terf1-002 protein_coding Mus_musculus 0 398
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.000005 58
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.000005 58

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