C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FYVE, RhoGEF and PH domain containing 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000285046 FGD5-001 ENSG00000154783 9606 + 3:14818962-14934388 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderHeartLiverLungPlacentaENST00000285046
Transcript ID Adipose Adrenal Bladder Heart Liver Lung Placenta
ENST00000285046 15.815±0.00 8.790±0.00 3.536±0.00 1.662±0.00 3.714±0.00 8.870±4.56 13.179±1.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GJ CIL_0007GJ_0001 CGP 3:14675099-14934565
CIL_0005AG CIL_0005AG_0001 CGP 3:14818962-15053600

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 ISS ruffle
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0007010 ISS cytoskeleton organization
GO:0008360 ISS regulation of cell shape
GO:0030027 ISS lamellipodium
GO:0030036 ISS actin cytoskeleton organization
GO:0031267 ISS small GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043088 ISS regulation of Cdc42 GTPase activity
GO:0043547 ISS positive regulation of GTPase activity
GO:0046847 ISS filopodium assembly
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113466 Fgd5-201 protein_coding Mus_musculus 0 2634
ENSMUST00000089334 Fgd5-001 protein_coding Mus_musculus 0 2634

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