C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ISL LIM homeobox 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000290759 ISL2-001 ENSG00000159556 9606 + 15:76336724-76342476 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonLungOvaryTestisENST00000290759
Transcript ID Brain Breast Colon Lung Ovary Testis
ENST00000290759 0.038±0.00 0.145±0.00 0.290±0.13 0.136±0.00 0.145±0.00 0.558±0.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000248 CIL_000248_0001 CGP 15:76215355-76342476
CIL_000245 CIL_000245_0001 CGP 15:76336724-76905444

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 ISS:IEA DNA binding
GO:0005622 IEA intracellular
GO:0005634 IC nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0021520 IEA spinal cord motor neuron cell fate specification
GO:0021524 IEA visceral motor neuron differentiation
GO:0031290 IEA retinal ganglion cell axon guidance
GO:0043565 IEA sequence-specific DNA binding
GO:0045665 IEA negative regulation of neuron differentiation
GO:0048663 IEA neuron fate commitment
GO:0048666 TAS neuron development
GO:0048935 TAS peripheral nervous system neuron development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000034869 Isl2-001 protein_coding Mus_musculus 0 1906
ENSMUST00000114290 Isl2-002 nonsense_mediated_decay Mus_musculus 0 918
ENSMUST00000164373 Isl2-003 nonsense_mediated_decay Mus_musculus 0 896
ENSMUST00000165302 Isl2-005 retained_intron Mus_musculus 0 660
ENSDART00000055936 isl2b-201 protein_coding Danio_rerio 0 649
ENSMUST00000175950 Isl2-004 protein_coding Mus_musculus 0 590

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