C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000293379 ITGA5-001 ENSG00000161638 9606 - 12:54395261-54419460 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000293379
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000293379 41.031±0.00 36.868±0.00 0.973±0.00 2.650±2.30 11.762±6.05 28.705±25.23 9.219±6.97 9.119±5.48 18.883±9.85 62.113±56.50 6.993±4.94 16.472±8.78 138.837±52.44 8.459±7.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000031 CIL_000031_0001 CGP 12:54369133-54419460
CIL_00003E CIL_00003E_0001 CGP 12:54395261-54473602

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 TAS angiogenesis
GO:0001726 TAS ruffle
GO:0005154 IEA epidermal growth factor receptor binding
GO:0005161 TAS platelet-derived growth factor receptor binding
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0007044 IEA cell-substrate junction assembly
GO:0007155 TAS cell adhesion
GO:0007157 IEA heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0007613 IEA memory
GO:0008305 IEA integrin complex
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0016032 IEA viral process
GO:0030198 TAS extracellular matrix organization
GO:0030335 IEA positive regulation of cell migration
GO:0030949 TAS positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031589 IMP cell-substrate adhesion
GO:0032587 IDA ruffle membrane
GO:0033631 IEA cell-cell adhesion mediated by integrin
GO:0034113 IMP heterotypic cell-cell adhesion
GO:0035313 IEP wound healing, spreading of epidermal cells
GO:0035987 IMP endodermal cell differentiation
GO:0043184 TAS vascular endothelial growth factor receptor 2 binding
GO:0045202 IEA synapse
GO:0046872 IEA metal ion binding
GO:0050731 IMP positive regulation of peptidyl-tyrosine phosphorylation
GO:0050839 IEA cell adhesion molecule binding
GO:0050900 TAS leukocyte migration
GO:0071062 TAS alphav-beta3 integrin-vitronectin complex
GO:2000811 IMP negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023128 Itga5-201 protein_coding Mus_musculus 0 4421

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