C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000296315 ARHGEF3-001 ENSG00000163947 9606 - 3:56727418-56801967 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000296315
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000296315 5.725±0.00 4.720±0.00 5.157±2.05 2.412±2.06 5.752±0.00 2.277±0.00 8.977±8.80 0.496±0.00 6.824±4.20 2.124±0.00 7.166±2.90 7.706±0.48 9.468±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UE CIL_0007UE_0001 VISTA 3:56468385-57070064

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005622 IDA intracellular
GO:0005829 TAS cytosol
GO:0007264 TAS small GTPase mediated signal transduction
GO:0007266 TAS Rho protein signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0043065 TAS positive regulation of apoptotic process
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000049206 Arhgef3-201 protein_coding Mus_musculus 0 1864

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