C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: high mobility group box 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000296503 HMGB2-001 ENSG00000164104 9606 - 4:173331695-173335125 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000296503
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000296503 0.367±0.00 1.826±0.32 0.983±0.00 4.252±0.00 1.206±0.00 0.639±0.00 0.529±0.00 2.207±0.00 0.675±0.00 5.877±1.57 23.901±15.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00007T CIL_00007T_0002 CGP 4:173168753-173335125
CIL_0008VG CIL_0008VG_0001 VISTA 4:173198350-173802625
CIL_0008BZ CIL_0008BZ_0001 VISTA 4:173215162-173815719

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000793 IDA condensed chromosome
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0003677 IEA:IMP DNA binding
GO:0003684 IDA damaged DNA binding
GO:0003690 ISS double-stranded DNA binding
GO:0003697 ISS single-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IEA:IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006265 ISS DNA topological change
GO:0006288 IDA base-excision repair, DNA ligation
GO:0006309 TAS apoptotic DNA fragmentation
GO:0006325 NAS chromatin organization
GO:0006334 NAS nucleosome assembly
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0007283 IEA spermatogenesis
GO:0007289 IEA spermatid nucleus differentiation
GO:0008301 IDA DNA binding, bending
GO:0008584 IEA male gonad development
GO:0019904 IEA protein domain specific binding
GO:0032075 IDA positive regulation of nuclease activity
GO:0033151 ISS V(D)J recombination
GO:0042056 IDA chemoattractant activity
GO:0043234 IDA protein complex
GO:0043388 IDA positive regulation of DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045648 IMP positive regulation of erythrocyte differentiation
GO:0045654 IMP positive regulation of megakaryocyte differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048545 IEA response to steroid hormone
GO:0050786 IGI RAGE receptor binding
GO:0050918 IDA positive chemotaxis
GO:0051103 ISS DNA ligation involved in DNA repair
GO:0060326 IDA cell chemotaxis
GO:0071222 IEP cellular response to lipopolysaccharide
GO:1902042 IEA negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000067925 Hmgb2-201 protein_coding Mus_musculus 0 1208
ENSMUST00000122151 Gm13237-001 processed_pseudogene Mus_musculus 0 797
ENSMUST00000121816 Gm13232-001 processed_pseudogene Mus_musculus 0 784
ENSMUST00000118441 Gm13160-001 processed_pseudogene Mus_musculus 0 743
ENSMUST00000118554 Gm13167-001 processed_pseudogene Mus_musculus 0 708
ENSMUST00000119295 Gm14098-001 processed_pseudogene Mus_musculus 0 579

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